摘要
用淫羊藿蜂胶佐剂0.2mL和0.4mL分别对3日龄雏鸡皮下注射,并于24日龄时以相同剂量重复注射1次,以注射后不同时间检测鸡腹腔巨噬细胞的吞噬活性;对28日龄小白鼠隔日皮下注射淫羊藿蜂胶佐剂0.2mL,并以环磷酰胺为对照。试验结果表明,淫羊藿蜂胶佐剂能显著提高雏鸡腹腔巨噬细胞的吞噬活性,其中0.4mL剂量组明显优于0.2mL剂量组;对小白鼠腹腔巨噬细胞的细胞毒效应能明显增强,并能拮抗环磷酰胺的免疫抑制作用。
Chicks were subcutaneously
injected with EPA at dose of 0.2 mL and 0.4 mL at the age of 3 days respectively and were
boosted at the same dosages at the age of 24 days and then the phagocytosis activities of the
celiac macrophages were measured at the various periods after injection of EPA. 28 dayold
mice were subcutaneously injected with EPA at a dosage of 0.2 mL every other day and
Cyclophosphamide was served as the control. The trial results revealed that the administration
of EPA to chicks and mice was able to elevate phagocytosis activities of the celiac
macrophages in the chicks of which the phagocytosis activity of the 0.4 mL dosage group was
obviously higher than that of the 0.2 mL dosage group, and to increase cytotoxic effect of the
celiac macrophages in the mice very much and to antagonise the immunosuppression of
cyclophosphamide for mice.
出处
《中国兽医科技》
CSCD
1999年第5期8-10,共3页
Chinese Journal of Veterinary Science and Technology
基金
国家自然科学基金