摘要
目的调查慢性乙肝患者的抑郁状态,探讨在药物治疗的基础上辅以心理干预对其疗效的影响。方法采用汉密尔顿抑郁量表和自尊量表筛查52例慢性乙肝患者,对有抑郁症状的患者予以心理干预治疗。4周后,重新测量两个量表,对患者的心理状态进行评定。结果 49名慢性乙肝患者有抑郁症状,检出率高达94%。三因素重复测量ANOVA分析结果如下:心理干预的主效应显著[F(1,45)=131.25,P<0.0001];心理干预与患者来源交互作用显著[F(1,45)=5.25,P=0.03],表现为农村和城镇患者的抑郁程度在治疗前存在差异趋势,但治疗后均得到改善,抑郁程度无差异。结论经过药物及心理干预治疗后,患者的抑郁症状明显减轻,而患者的自尊程度显著增高。采取有针对性的心理干预措施,能使慢性乙肝患者达到更好的治疗效果。
Objective To investigate the depression status in patients with chronic hepatitis B,and the effect of psychological intervention combined with drug on depression status.Methods Fifty-two patients with chronic hepatitis B were given a structural interview based on Hamilton depression scale and self-esteem scale.The patients with depression symptoms were treated with psychological intervention based on drug treatment.After 4 weeks,the two scales were determined again to evaluate the psychological states of the patients.Results Of 52 patients with chronic hepatitis B,49（94%）had depressive symptoms.Three factor[2（gender）×2（population）×2（before/after treatment）]ANOVA results showed that the main effect of psychological intervention was significant[F（1,45）=131.25,P=0.000];and that the interaction of psychological intervention and patient source was significant[F（1,45）=5.25,P=0.03].Conclusion After drug treatment and psychological intervention,the patient＇s depressive symptoms are relieved and the self-esteem level increases.Patients with chronic hepatitis B can achieve a better effect after targeted psychological interventions.
出处
《山西医科大学学报》
CAS
2010年第9期761-764,共4页
Journal of Shanxi Medical University
基金
国家高技术研究发展计划(863)资助项目(2006AA02A410)
北京市丰台区科技项目(2009-39)
关键词
慢性乙肝
抑郁
心理干预
chronic hepatitis B
depression
psychological intervention
