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ApoE基因对急性缺血性脑卒中的影响:磁共振成像研究 被引量:2

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摘要 ApoEε4等位基因对急性缺血性脑卒中兼具危害和保护效应。ApoEε4等位基因的危害效应表现在梗死体积增加更多,脑组织损伤的血供阈值低,病人临床愈后与影像学发现不成比例。但是ApoEε4等位基因携带者有更完好的侧支循环。涉及ApoEε4等位基因和临床愈后的研究显示,危害和保护效应可能会相互抵消。在今后的缺血性脑卒中影像学和临床愈后研究中,ApoEε4等位基因干扰效应需要加以控制。
出处 《国际医学放射学杂志》 2010年第5期456-458,共3页 International Journal of Medical Radiology
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