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瑞芬太尼在清醒开颅手术中的应用 被引量:5

Application of remifentanil in awake craniotomy surgery
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摘要 目的观察瑞芬太尼在清醒开颅手术中的应用,探讨其有效性和安全性。方法回顾性分析2007~2009年行颞叶或者额叶肿瘤切除手术的患者24例,年龄20~60岁,性别不限,ASAⅡ~Ⅲ级,以0.2%罗哌卡因沿切口行局部浸润麻醉,术中以微量泵持续静脉注射瑞芬太尼0.05~0.1μg/(kg·min),保持患者意识清醒。术中监测血流动力学变化和并发症情况,功能区监测采用连续计数法,记录术后患者对手术过程的满意程度。结果患者均能在清醒状态下配合完成手术,术中血流动力学稳定,未见明显并发症和不良手术记忆,满意度良好。结论在良好的局部浸润麻醉下,瑞芬太尼可以安全地应用于清醒开颅手术,且血流动力学稳定,患者耐受良好。 Objective To investigate availability and safety of remifentanyl in awake craniotomy. Methods 24 patients undergoing temporal lobe or frontal lobe tumor resection were randomly anesthetized with 0.2% ropivacaine in complete And remifentanyl was injected intravenously with micropump in 0.05-0.1μg/( kg·min). The hemodynamic changes and complications during operation were monitored. The patients were monitored for language cortex localization by phonated number counting and the satisfaction for surgical procedure was evaluated. Results All surgerys could be completed in a conscious state for patients with stable haemodynamics;There were no conspicuous complication and bad memory to operation, and satisfaction rate was well. Conclusion Remifentanyl could be used securely in awake craniotomy surgery on the base of good local anesthesia, and hemodynamics were stable and the patients were well tolerated.
出处 《中国医学创新》 CAS 2010年第22期39-40,共2页 Medical Innovation of China
关键词 瑞芬太尼 清醒麻醉 开颅 Remifentanyl Awake anesthesia Brain tumor
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参考文献6

  • 1张忠,江涛,谢坚,刘福生,韩如泉,陈新忠,乔慧,李子孝.唤醒麻醉和术中功能定位切除语言区胶质瘤[J].中华神经外科杂志,2007,23(9):643-645. 被引量:39
  • 2Olsen KS.The asleep-awake technique using propofol-remifentanil anaesthesia for awake craniotomy for cerebral tumours.Eur J Anaesthesio,2008,25(8):662-669.
  • 3赵高峰,张兴安,施冲,吴群林,徐波.靶控输注异丙酚复合瑞芬太尼或芬太尼全静脉麻醉[J].广东医学,2004,25(7):765-767. 被引量:103
  • 4Demirbilek S,Ganidagli S,Aksoy N,et al.The effects of remifentanil and alfentanil-based total intravenous anesthesia (TIVA)on the endocrine response to abdominal hysterectomy.Clin Anesth,2004,16(5):358-363.
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