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同型半胱氨酸与复发自然流产的关系 被引量:2

Homocysteine and recurrent spontaneous abortion
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摘要 目的了解孕妇血清同型半胱氨酸水平与不明原因复发性流产的关系。方法将检测对象分为3组:复发性流产组40例(A组),其中早孕流产组25例(A1组)),中孕流产组15例(A2组);正常妊娠组B组,其中正常早早孕组30例(B1组),正常中孕组30例(B2组);正常育龄妇女组30例(C组),采用循环酶法检测各组血清同型半胱氨酸水平。结果 A组与B组及C组血清同型半胱氨酸水平比较,差异有显著性(P<0.01);A1组血清同型半胱氨酸水平与A2组比较,差异有显著性(P<0.01);而B1与B2组血清同型半胱氨酸水平比较,差异无显著性(P>0.05);A1组与B1组比较,差异有显著性(P<0.01);A2组与B2组比较,差异有显著性(P<0.01)。结论同型半胱氨酸与复发性流产发病存在密切相关,高同型半胱氨酸水平可以作为不明原因复发性流产的一个危险因素。 Objective To understand the relationship of the serum homocysteine(Hcy) levels with unexplained recurrent spontaneous abortion.Methods The detect objects was divided into 3 groups.There were 40 patients in recurrent spontaneous abortion group(A group),25 cases in early pregnancy abortion group(A1group) ),15cases in pregnancyspontaneous abortion group(A2 group);normal pregnancy,including 30 cases of normal early pregnancy group(B1 group),normal in pregnant group.B group was(B2 group);30 cases in normal childbearing age Women Group(C).The homocysteine levels were detected by cyclic enzymatic in each groups.Results The serum Hcy level of A group and B group and C,the difference was significant(P <0.01 ).Al and A2 serum Hcy levels compared,the difference was significant(P<0.01 );The Bl and B2 levels of serum Hcy comparison,the difference was not statistically significant(P >0.05 );comparing A1 group and B1 group,the difference was significant(P<0.01).A2 group and B2 group,the difference was a significant(P <0.01 ).Conclusion There is a close relationship between homocysteine and the incidence of recurrent spontaneous abortion,high homocysteine levels can be used as a risk factor of unexplained recurrent spontaneous abortion.
作者 杨松娣
出处 《中国医学创新》 CAS 2010年第22期6-7,共2页 Medical Innovation of China
关键词 复发性流产 早早孕 中孕 同型半胱氨酸 Recurrent spontaneous abortion Early pregnancy In pregnancy Homocysteine
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