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医院感染光滑念珠菌临床分布及其耐药性分析 被引量:2

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摘要 目的对医院感染临床标本中分离出的光滑念珠菌临床分布和耐药性分析,了解其临床感染现状,为临床提供病原学诊断和合理使用抗真菌药物的依据。方法对2007~2009年微生物实验室分离鉴定得到的光滑念珠菌,采用ATBFUNGUS3真菌药敏板条进行药敏实验,并对临床分布和耐药性进行统计分析。结果 2007~2009年光滑念珠菌的检出率呈逐年上升趋势,分别为15.6%、16.3%、21.8%,临床分布以痰标本为主,其次是尿液和大便标本。光滑念珠菌对两性霉素B、伏立康唑,5-氟胞嘧啶的敏感率较高,平均敏感率分别是100%,95.8%,97.9%;其次为氟康唑,平均敏感率87.3%;伊曲康唑的抑菌效果则较差,仅为55.4%。结论 2007~2009年光滑念珠菌的临床感染率呈上升趋势,因此,临床微生物实验室要加强对光滑念珠菌的分离培养和药敏实验,指导临床合理用药,有效控制和减少真菌感染。
出处 《中国现代药物应用》 2010年第18期152-154,共3页 Chinese Journal of Modern Drug Application
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