摘要
为了进一步探讨口腔扁平苔藓（ＯＬＰ）与幽门螺旋杆菌（ＨＰ）的关系，本研究应用非放射性ＤＩＧ系统的原位杂交技术对２０例ＨＰ－ＰＣＲ阳性的ＯＬＰ患者作ＨＰ－ＤＮＡ的检测。结果显示：在２０例ＯＬＰ的损害组织中，１８例为ＨＰ－ＤＮＡ阳性，２例为阴性，而对照组均为阴性。结果提示ＯＬＰ损害组织中ＨＰ所致的病理变化可能是某些ＯＬＰ的发病基础。
In order to discuss the relationship of oral lichen
planus(OLP) and helicobacter pylori(HP),in situ hybridization was applied to detect HP DNA in the
lesions of 20 OLP cases who were HP PCR positive. The result showed that 18 of 20 OLP cases
had positiveness of HP DNA and 2 negativeness. It is indicated that HP in the lesions of OLP may
result in pathological change which may be the pathogenic basis of OLP.
出处
《临床口腔医学杂志》
1999年第2期88-90,共3页
Journal of Clinical Stomatology
基金
深圳建安医药公司资助
关键词
口腔扁平苔藓
幽门螺旋杆菌
原位杂交
Oral Lichen
Planus Helicobacter Pylori In Situ Hybridization
