摘要
目的：比较丁咯地尔与脉络宁治疗脑梗死的疗效。方法：６０例脑梗死病人，其中３０例采用丁咯地尔２００ｍｇ加入５％葡萄糖注射液５００ｍＬ，静脉滴注（静滴），ｑｄ，１４ｄ为一个疗程。另３０例为对照组，采用脉络宁２０ｍＬ加入５％葡萄糖注射液５００ｍＬ，静滴，ｑｄ，１４ｄ为一个疗程。结果：丁咯地尔组总有效率８７％，显效率６３％。脉络宁组总有效率６４％，显效率３０％（Ｐ＜０．０５）。丁咯地尔对脑循环动力学有显著改善（Ｐ＜０．０１）。该药不良反应较少。结论：丁咯地尔治疗脑梗死的疗效优于脉络宁。
AIM: To compare buflomedil (Buf) vs Mailuoning (MLN) in treating cerebral infarction. METHODS: Thirty patients with cerebral infarction treated with Buf 200 mg in 5% glucose injection 500 mL, iv drip, qd for 14 d. Another 30 patients were treated with MLN 20 mL in 5% glucose injection 500 mL, iv drip, qd for 14 d. RESULTS: Buf group yielded a total response rate 87% and excellent rate 63%, which were higher than those of MLN group 64% and 30%( P <0.05), respectively. Buf also improved brain circulation dynamics ( P < 0.01), and adverse reaction was mild. CONCLUSION: Buf is better than MLN in treating cerebral infarction.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
1999年第3期149-150,共2页
Chinese Journal of New Drugs and Clinical Remedies
关键词
丁咯地尔
脉络宁
治疗
脑梗塞
buflomedil
Mailuoning
cerebral infarction
vasodilator agents
blood flow velocity
color Doppler ultrasonography
