摘要
目的铜针留置术治疗海绵状血管瘤等血管性疾病,因其特有的优点,临床已开展应用。为了解铜针留置于血管内所发生的病理变化。方法我们用60只家兔的中央静脉行铜针留置,并与不锈钢针留置比较观察血管腔内所发生的病理变化及超微结构改变。结果铜针留置后7天内为急性炎症过程及血栓形成,14天后形成异物性肉芽肿组织,28～60天后瘢痕组织纤维化,血管结构消失。不锈钢针留置诱发的炎症过程轻,血栓形成迟且较小。结论铜针治疗血管性疾病优于不锈钢针。
Objective The clinical application of copper needle insertion has been proceeded satis- factorily for peripheral vascular disorders.This work was to study the mechanism of the copper needle in- sertion on a pathological basis.Methods Sixty rabbits were used in the experiments.The copper needle or the stainless steel needle was inserted into the ear central vein of the animal.Then the specimens of the central vein including its surrounding tissue were taken for light and electron microscopic examinations. Results At 7 days after copper needle insertion,acute inflammation reaction of the venous wall and vas- cular thrombosis were revealed in the specimens.At 14 days,giant cells granuloma and destruction of the venous wall were seen.After 28 days to 2 months,granuloma and the residual destroyed venous wall were gradually absorbed and firbosis resulted.The vascular inflammation and thrombosis caused by stainless steel needle insertion was slight and slow.Conclusion Copper needle treatment for vascular disorders is superi- or to the stainless steel needle.
