期刊文献+

阿托伐他汀与曲美他嗪合用治疗冠状动脉粥样硬化性心脏病研究进展 被引量:9

暂未订购
导出
摘要 众所周知,HMG—CoA还原酶抑制药(他汀类)使降低高胆同醇(Tc)的治疗发生了革命性变化,大多数他汀类药物能使主要冠脉事件的风险减少30%。但是,高脂血症患者尽管用了他汀类药物治疗,仍有心血管疾病发生。因此,需要与其他药物合用加强疗效。Syrkin等怛0在接受辛伐他汀和氯吡格雷治疗的心绞痛和(或)跛行患者中,加用曲美他嗪(TMZ)后,心绞痛改善了46.7%,
出处 《武警医学》 CAS 2010年第9期737-740,共4页 Medical Journal of the Chinese People's Armed Police Force
  • 相关文献

参考文献24

  • 1Fazio S.Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease:a role for combination fibrate therapy[J].Clin Ther,2008,30(2):294-306.
  • 2Syrkin A L,Artiukhina E G,Kanorskiǐ S G,et al.Antiischemic efficacy of trimetazidine in patients with intermittent claudication and effort angina[J].Kardiologiia,2003,43(7):49-52.
  • 3Chatterjee S,Berliner J A,Subbanagounder G G,et al.Identification of a biologically active component in minimally oxidized low density lipoprotein (MM-LDL) responsible for aortic smooth muscle cell proliferation[J].Glycoconj J,2004,20(5):331-338.
  • 4Dhaliwal B S,Steinbrecher U P.Scavenger receptors and oxidized low density lipoproteins[J].Clin Chim Acta,1999,286(1-2):191-205.
  • 5Miller Y I,Choi S H,Fang L,et al.Lipoprotein modification and macrophage uptake:role of pathologic cholesterol transport inatherogenesis[J].SubcellBiochem,2010,51:229-235.
  • 6Puccetti L,Bruni F,Pasqui A L,et al.Genetic influence in antithrombotic actions of atorvastatin in hypercholesterolaemia[J].Eur J Clin Invest,2008,38(1):11-16.
  • 7Wilensky R L,Macphee C H.Lipoprotein-associated phospholipase A(2) and atherosclerosis[J].Curr Opin Lipidol,2009,20(5):415-420.
  • 8li D,Mehta J l.Upregulation of endothelial receptor for oxidized ldl(lox-1)by oxidized ldl and implications in apoptosis of human coronary artery endothelial cells:evidence from use of antisense lox-1 mrna and chemical inhibitors[J].Arteriopscler thromb vasc biol,2000,20:1116-1122.
  • 9Kaesemeyer W H,Caldwell R B,Huang J,et al.Pravastation sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions[J].J Am Coll Cardiol,1999,33:234-241.
  • 10Wong B,Lumman WB,Smith S M,et al.Statins suppress tgp-1 cell migration and secretion of matrix metallopoteinase 9 by inhibiting geranylgeranylation[J].J leukoebiol,2001,69:959-962.

二级参考文献45

共引文献46

同被引文献62

  • 1Park S J,Kim Y H.Current status of percutaneous coronary intervention with drug-eluting stents in Asia[J].Circulation,2008,118(25):2730-2737.
  • 2Bekkers SC,Yazdani S K,Virmani R,et al.Microvascular obstruction:underlying pathophysiology and clinical diagnosis[J].J Am Coll Cardiol,2010,55(16):1649-1660.
  • 3Lee C H,Tse H F.Microvascular obstruction after percutaneous coronary intervention[J].Catheter Cardiovasc Interv,2010,75(3):369-377.
  • 4Patti G,Pasceri V,Colonna G,et al.Atorvastatin pretreatment improves outcomes in patients with acute coronary syndromes undergoing early percutaneous coronary intervention:results of the ARMYDA-ACS randomized trial[J].J Am Coll Cardiol,2007,49(12):1272-1278.
  • 5Bahrmann P,Figulla H R,Wagner M,et al.Detection of coronary microembolisation by Doppler ultrasound during percutaneous coronary interventions[J].Heart,2005,91(9):1186-1192.
  • 6Pasceri V,Patti G,Nusca A,et al.Randomized trial of atorvastatin for reduction of myocardial damage during coronary intervention:results from the ARMYDA (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) study[J].Circulation,2004,110(6):674-678.
  • 7Briguori C,Visconti G,Focaccio A,et al.Novel approaches for preventing or limiting events (Naples) Ⅱ trial:impact of a single high loading dose of atorvastatin on periprocedural myocardial infarction[J].J Am Coll Cardiol,2009,54 (23):2157-2163.
  • 8Banach M,Rysz J,Goch A,et al.The role of trimetazidine after acute myocardial infarction[J].Curr Vasc Pharmacol,2008,6(4):282-291.
  • 9Bonello L,Sbragia P,Amabile N,et al.Protective effect of an acute oral loading dose of trimetazidine on myocardial injury following percutaneous coronary intervention[J].Heart,2007,93(6):703-707.
  • 10Park S J, Kim YH. Current status of percutaneous coronary intervention with drug-eluting stents in Asia. Circulation,2008,118:2730-2737.

二级引证文献98

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部