摘要
目的：评价我国ＯＴＣ药物和指导其合理应用。方法：对６５３例抗感冒药致不良反应的临床报道进行文献分析。结果：６５３例病例涉及１６种抗感冒药，其中感冒通致不良反应最多（７４．２７％），主要表现为血尿和消化道出血；其次为康泰克（１２．８６％），主要为心血管系统反应（１００．００％）。４例因过量服用抗感冒药导致死亡。Ａ型反应５８２例，Ｂ型反应７１例。病例年龄在４月～７７岁之间，主要为０岁～１４岁（７１．５％）。结论：抗感冒药在使用时应不要过量，不要滥用，避免因不合理应用造成对人体的伤害。
OBJECTIVE:To evaluate OTC drugs and instruct it’s rational use.METHODS:We carried out an analysis on 653 cases of ADRs caused by anti cold drugs reported in literature.RESULTS:The reported 653 cases of ADRs involved 16 kinds of anti cold drugs.The ADRs mostly involved the use of Gan Mao Tong(74.27%) and Contac(12.86%).Hematuria accounted for 83.71% of all the reported ADRs caused by Gan Mao Tong.The ADRs on cardiovascular system accounted for 100.0% of all the reported ADRs caused by Contac.There were four fatal cases caused by overdose of anti cold drugs.There were 582 cases of type A reaction and 71 cases of type B reaction.The age of the patients ranged from 4 months to 77 years and most of them were 0～14 years old.CONCLUSIONS:We should pay attention to the overdose and abuse use of anti cold drugs,so as to avoid damaging the body by irrational drug administration.
出处
《中国药房》
CAS
CSCD
1999年第3期132-134,共3页
China Pharmacy
