摘要
目的研究早期短时连续性静-静脉血液透析滤过(SCVVHDF)对重症急性胰腺炎(SAP)合并急性肺损伤(ALI)的治疗效果。方法选取2006年9月—2009年12月我院急诊ICU收治的36例合并ALI的SAP患者,分为SCVVHDF组和对照组,对比分析两组患者生命体征、氧合指数、急性生理和慢性健康状况评分系统Ⅱ(APACHEⅡ)评分、机械通气时间、ICU住院时间及病死率。结果治疗后24 h、48 h、72 h、120 h SCVVHDF组患者心率与呼吸频率较对照组明显降低,差异有统计学意义(P<0.05)。治疗后24 h、48 h SCVVHDF组患者体温较对照组明显降低,差异有统计学意义(P<0.05)。治疗后24 h、48 h、72 h、120 h SCVVHDF组氧合指数较对照组明显升高,差异有统计学意义(P<0.05)。治疗后72 h、120 h SCVVHDF组APACHEⅡ评分较对照组明显降低,差异有统计学意义(P<0.05)。SCVVHDF组机械通气时间及ICU住院时间较对照组明显缩短,差异有统计学意义(P<0.05)。SCVVHDF组病死率较对照组明显下降,差异有统计学意义(P<0.05)。结论 SCVVHDF治疗能促进SAP合并ALI患者肺功能的恢复,减少机械通气时间,缩短ICU住院天数,减少住院病死率,是一项重要的辅助治疗措施。
Objective To research the treatment effectiveness of early short continuous veno-venous hemodiafiltration（SCVVHDF） on severe acute pancreatitis（SAP） with acute lung injury（ALI）.Methods Thirty-six SAP patients with ALI admitted to emergency ICU from September 2006 to December 2009 were divided into groups SCVVHDF and control.The vital sign,oxygenation index,APACHE II scores,mechanical ventilation time,length of ICU stay and mortality were analyzed comparatively.Results The heart rate and respiratory were significantly lower in group SCVVHDF than in control at hour 24,48,72,120 after treatment（P0.05）;the temperature lower at hours 24,48（P0.05）;oxygenation index higher at hours 24,48,72,120（P0.05）;APACHE II scores lower at hours 72,120（P0.05）;mechanical ventilation time and length of ICU stay shorter（P0.05）;mortality lower（P0.05）.Conclusion SCVVHDF,promoting the recovery of lung function,shortening length of ICU stay and reducing hospital mortality,is an important complementary treatment for SAP patients ALI.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第24期2664-2666,共3页
Chinese General Practice
基金
江西省卫生厅基金资助项目(20091111)
