摘要
目的:探讨MR灌注加权成像(PWI)在单发脑转移瘤与高级别胶质瘤鉴别诊断中的价值。方法:对单发转移瘤(n=12)或高级别星形细胞瘤(n=22)的MRPWI特征进行回顾性分析。结果:脑PWI中,高级别胶质瘤在对比剂首过后信号强度恢复快速,而转移瘤在对比剂首过后信号回复缓慢且明显不足。高级别胶质瘤与转移瘤的rCBV值无显著差异;但高级别胶质瘤瘤旁及瘤周rCBV值明显高于转移瘤。结论:MR灌注成像能显示肿瘤及瘤周区域血流灌注特性,对单发性脑转移瘤和高级别胶质瘤的鉴别诊断有潜在应用价值。
Objective： To determine the value of MR perfusion-weighted imaging （PWI） in the differentiation of solitary cerebral metastatic tumor and high-grade gliomas. Methods： MR PWI features of solitary cerebral metastatic tumors （n=12） or high-grade gliomas （n=22） were compared respectively. Results： After the first pass of contrast agent in PWI, high-grade gliomas demonstrated a rapid recovery of signal intensity; while time-signal-intensity curve （SIC） of metastatic tumors showed a placid and incomplete recovery of signal intensity. There was no significant difference between the rCBV values of highgrade gliomas and metastatic tumors. However, the para- and peri-tumoral rCBV values of high-grade gliomas were significantly higher than that of metastatic tumors. Conclusion： MR perfusion-weighted imaging is a potential tool to differentiate solitary cerebral metastatic tumor from high-grade gliomas by depicting the hemodynamic features of tumors and peritumoral areas.
出处
《中国临床医学影像杂志》
CAS
北大核心
2010年第9期609-612,共4页
Journal of China Clinic Medical Imaging
关键词
脑肿瘤
神经胶质瘤
肿瘤转移
磁共振成像
Brain neoplasms
Glioma
Neoplasm metastasis
Magnetic resonance imaging
