摘要
目的:研究急性颅脑损伤患者早期凝血-纤溶功能变化与颅内出血和预后的关系。方法:检测196例急性颅脑损伤患者24h内的格拉斯哥昏迷评分(GCS)、凝血酶原时间(PT)、凝血酶时间(TT)、部分活化凝血酶原时间(APTT)、D-二聚体浓度(D-D),作2次或多次CT扫描,分析颅脑损伤患者急性期凝血-纤溶功能的变化与颅内出血和预后的关系。结果:196例颅脑损伤患者的早期D-二聚体浓度变化以颅内血肿患者最为明显,并与颅脑损伤严重程度和预后密切相关。结论:颅脑损伤早期存在凝血-纤溶功能变化,颅脑损伤者早期应密切检查凝血-纤溶功能,如有异常应及时行动态头颅CT检查以及早发现迟发性颅内血肿,提高临床救治水平。
Objective：Study the relationship between early change of coagulation-fibrinolysis function and prognosis in acute brain traumatic patients.Methods： The GCS,prothrombin time（PT）,thrombin time（TT）,activated partial thromboplastine time（APTT）,D-dimer（D-D） and CT in 196 acute brain traumatic patients were measured.The relationship between the change of coagutation-fibridysis function and the prevanlence of intracranial hematoma was analyzed.Results： The D-D change was most significant in brain hematoma patients and was closely related to the prognosis.Conclusions： The coagulation-fibrirolysis function changed early in brain traumatic patients and shonld be detected closely.CT scan can detect delayed intracranial hematoma.
出处
《中国临床医学》
2010年第4期487-488,共2页
Chinese Journal of Clinical Medicine
关键词
颅脑损伤
颅内血肿
预后
Brain tranma
Intracranial hematoma
Prognosis
