摘要
目的为了观察人工肝支持系统在肝移植围手术期中的应用情况。方法对１例晚期肝硬变伴小肝癌患者施行同种异体原位肝移植，术前术后共进行８次人工肝支持系统治疗，移植术中无肝期采用体外静脉转流技术，术后应用甲基泼尼松龙和环孢素Ａ进行免疫抑制。结果患者术后早期恢复顺利，但手术后２１天死于颅内出血。结论认为术前使用人工肝支持系统能改善患者一般情况，使更易耐受手术，并可在急性肝功能衰竭患者等待供肝时使用；术后使用能改善患者生理紊乱状况。
Objective To investigate the application of artificial liver support system during the perioperation of orthotopic liver transplantation. Methods One patient with end stage liver cirrhosis with liver cancer successfully underwent orthotopic liver transplantation. The patient received artificial liver support system (ALSS) treatment 8 times before and after operation. The recipients' operation was performed under the veno venous bypass procedure. The double drug immunosuppressive regimen , methylprodnisolone and cyclosporine A, was used after operation.Results The patient had a smooth recovery in the early stage and died of intracerebral hemorrhage at the 21st postoperative day.Conclusion ALSS treatment can improve general conditions of the patient before operation, and correct physiological disturbances and help to survive during immune rejection after operation.
出处
《中华器官移植杂志》
CAS
CSCD
1999年第2期73-75,共3页
Chinese Journal of Organ Transplantation
