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肿瘤的生物治疗进展 被引量:9

Progress in biotherapy of tumor
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摘要 肿瘤的治疗分为传统的手术、放射治疗、化疗和生物治疗。生物治疗是肿瘤治疗的第四种模式,通过调动宿主的天然防御机制或给予天然产生的针对性、靶向性很强的物质,来干扰肿瘤的生物学行为和调节病人抗肿瘤免疫反应,实现对肿瘤的治疗。目前的研究和应用领域主要集中于肿瘤的基因治疗、免疫治疗、抗血管生成治疗、细胞因子治疗、病毒增殖治疗和联合治疗。本文从目前国内外实验研究和临床应用方面综述了肿瘤的生物治疗进展。 The treatment of tumor includes conventional surgery,radiation therapy,chemotherapy and biotherapy.As the fourth mode of tumor treatment,biotherapy interferes biological behavior of tumor and regulates immune response of patients to tumor by mobilizing the host's natural defense mechanism or giving naturally occurred substances with highly specific targeting property.Current research and applications focus on gene therapy,immune therapy,anti-angiogenesis therapy,cytokine therapy,viral proliferation treatment and combined treatment.This paper makes an overview of progress in tumor biotherapy from the current experimental study and clinical applications at home and abroad.
作者 张勤
出处 《药学服务与研究》 CAS CSCD 2010年第4期247-251,共5页 Pharmaceutical Care and Research
关键词 肿瘤 生物治疗 综述 tumor biotherapy review
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