摘要
目的探讨法舒地尔对有机磷农药中毒迟发性神经疾病(OPIND)的影响。方法 16例OPIND患者随机分为两组:对照组给予综合治疗;治疗组在此基础上加用法舒地尔,观察两组患者临床表现、神经电生理变化,判断临床疗效。结果与对照组比较,治疗组患者运动神经传导速度和感觉神经传导速度加快,神经F波潜伏期缩短,增加F波引出率,显著改善患者疗效能改善OPIND患者的神经功能,减轻临床症状(P<0.05)。结论临床应用法舒地尔能有效治疗OPIND。
Objective To investigate the effect of fasudil on the patients with organophosphate-induced delayed neuropathy（OPIND. Methods Sixtee patients with OPIND were randomly divided into two groups with 20 cases each.The patients in group A were treated with fasudil and conventional therapy,those in group B with conventional therapy only as the controls.Clinical manifestations and indexes of neuroelectrophysiology were measured and compared.Results Compared to group B,the velocity of nerve conduction was increased,nerve function was improved and clinical symptoms were relieved in group A.Conclusion Fasudil can effectively treat the patients with OPIND.
出处
《江苏医药》
CAS
CSCD
北大核心
2010年第16期1872-1874,共3页
Jiangsu Medical Journal
基金
徐州市科技局社会发展基金(XM08C091)
徐州医学院课题(09KJ09)
徐州医学院附属医院课题(2009016)
