3Simon RP, Niiro M, Gwinn R. Prior ischemic stress protects against experimental stroke [J ]. Neurosci Lett, 1993,163 : 135-137.
4Barone FC,White RF, Spera PA,et al. Ischemic preconditioning and brain tolerance: temporal histological and functional outcomes, protein synthesis requirement and interlukin-1 receptor antagonist and early gene expression[J]. Stroke, 1998,29 : 1937-1951.
5Longa EZ.Weinstein PR,Carson S,et a1.Reversible middle cerebral artery occlusion without crainietomy in rats[J].Stroke,1989,20(1):84—91.
6Menzies SA,Hoff JT,Betz AL,Middle cerebral artery occlusion in rats:a neurological and pathological evaluation of a reproducible model[J],Neurosurgery,1992,31:100—107.
7Kitagawa K,Matsumoto M,Kuwabara K,et a1.Ischemic tolerance phenomenon detected in various brain regions [J].Brain Res,1991,561(2):203-211.
8Krino T,Tsujita Y,Tamura A.Induced tolerance to ischemia in gerbil hippocampal neuron[J].J Cereb Blood Flow Metab,1991,11:299-307.
9Miyashita K,Abe H,Nakajima T,et a1.Induction of ischemic tolerance in gerbil hippocampus by pretreatment with focal ischemia[J].Neuroreport,1994,6:46—48.
10Sugawara T, Noshita N, Lewen A, et al. Neuronal expression of the DNA repair protein Ku 70 after ischemic preconditioning corresponds to tolerance to global cerebral ischemia[J]. Stroke,2001,32(10) : 2388-2393.
2Tel H. Frequency and its annual change of usage of antithrombotic agent and edarabone according to stroke subtype. Stroke databank [in Japanese]. Tokyo: Nakayama Shoten Company, Limited, 2005,80-81.
3Naritomi H. Research on the influences of muscle atrophy preven- tive therapy starting from the acute phase of cerebral infarction on chronic phase motor function [in Japanese. HealthLabour Science Research Grant, Comprehensive Research on Aging and Health. 2007 Overview Study Rep 2008.
4Osaka: Ministry of Health, Labour and Welfare of Japan, 2008 Wang PY,Kao CH,MuiMY, et al. Leukocyte infiltration in acute hemispheric ischemic stroke[J]. Stroke,1993,24:236-240.
5Kawase T, Mizukami M, Tazawa T, et al. Dynamic pathophysi- ology of cerebral infarction and revascularization. I: ischemic cere- bral edema [in Japanese]. No To Shinkei, 1982,34:1077-1083.
6Lodder J, Krijne-Kubat B, van der Lugt PJ. Timing of autopsy- mnfirmed hemorrhagic infarction with reference to eardioembolic stroke[J]. Stroke, 1988,19 : 1482-1484.
7Suzuki K. Pathology of cardioembolic stroke [in Japanese]. Ther Res, 2000,3 : 403-408.
8Houkin K, Ueno K, TadaM, et al. Arterial recanalization in acute stage of cerebral infarction [in Japanese ]. Neurol Med Chir (Tokyo) ,1987,27:295-301.
9Peters O, Back T, Lindauer U, et al. Increased formation of reac- tive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat[-J]. Cereb Blood Flow Metab, 1998,18t 196-205.
10Furuya D, Tanahashi N, Araki N, et al. Edaravone therapy initi- ated immediately after cardioembolic stroke and its effects on func- tional recovery[J]. Jpn J Stroke, 2006,28 : 291-296.
