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NF-kB在急性胰腺炎治疗研究中的进展及前景 被引量:3

Advancement and perspective of NF-kB in the research of acute pancreatitis
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摘要 急性胰腺炎是胰酶激活后引起胰腺组织自身消化所致的急性炎性介质反应,可诱发全身炎性介质反应,并恶化为多脏器功能衰竭,导致患者死亡.核转录因子κB在急性胰腺炎的发展中占据核心地位,它凋节了炎性因子和免疫蛋白的基因表达.本文就基于NF-κB的胰腺炎治疗作一综述. Acute pancreatitis is acute inflammation due to autodigestion of pancreatic tissue by trypsogen activation, can induce systemic inflammatory reaction,and deteriorate to be nonfunction and fatality. Nuclear factor kappa B seizes the coral position in the development of acute pancreatitis, regulates gene expression of inflammatory factors and immune protein. This article reviews the therapy of pancreatitis on account of NF-κB.
作者 朱含章 谢敏
出处 《国际外科学杂志》 2010年第9期621-624,共4页 International Journal of Surgery
关键词 急性胰腺炎 核转录因子-KB 治疗 Acute pancreatitis NF-κB Therapy
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