摘要
目的探讨Fibroscan与病理肝纤维化分级的符合率以及Fibroscan与二维超声的相关性，以便提高其诊断价值，从而减少慢性肝病患者肝活检的需要。方法对行过肝活检的23名住院病人使用Fibroscan对其进行肝硬度测量及二维超声检查，分析其三者间的相关性。结果病理各期与LSM值比较：F0～1期，符合率为62．5％，F1～2期，符合率为40．0％，F3—4期33.3％；F4期，符合率为50％。LSM值与二维超声比较：无明显或轻度纤维化组，符合率为92．8％。明显和严重纤维化组，符合率75．0％。肝硬化组：符合率为80．0％。二维超声与病理结果比较：F0～F2组：符合率92．9％；F3～F3～4组：符合率为100％；F4组：符合率100％。结论Fs对肝纤维化的诊断具有参考意义，尤其对区分F4期及非F4期作用比较明显，对于F0～F1期，FS还是能较好的体现与肝活检结果的相关性；只有在F2及F3-4期时，Fs的鉴别能力还有待验证。
Objective To investigate the coincidence between fibroscan and pathology in the staging of hepatic fibrosis, and the correlation between Fibroscan and two-dimensional ultrasound in order to improve its diagnostic value in patients with chronic liver disease and thus reduce the need for liver biopsy. Methods 23 patients who have received liver biopsy received fibroscan examination and two-dimensional ultrasound examination, then the correlation was analyzed. Results Comparison of pathological staging and LSM value： F0-1 period, consistent rate of 62.5%, F1-2 period, consistent rate of 40.0%, F3-4 period, 33.3%; F4 period, the rate was 50%. LSM value compared with the two-dimensional ultrasound： no or mild fibrosis group, the rate was 92.8%. Obvious and severe fibrosis, the rate was 75.0%. Cirrhosis： compliance rate was 80.0%. Comparison of two-dimensional ultrasound and pathological findings： F0-F2 group： consistent rate 92.9%; F3-F3-4 Group： coincidence rate was 100%; F4 group： consistent rate of 100%. Conclusions FS is useful for the diagnosis of liver fibrosis, especially to distinguish between F4 and non-F4; for the period of F0-F 1, FS, is correlated with liver biopsy results; only in the F2 and F3 -4 Time, FS＇s ability to identify remains untested.
出处
《世界感染杂志》
2010年第4期199-201,共3页
World Journal of Infection
关键词
FIBROSCAN
病理
二维超声
肝纤维化
肝硬化
FibroScan
pathology two-dimensional ultrasound
liver fibrosis
hepatic cirrhosis
