摘要
目的观察轻身降脂饮对颈动脉粥样硬化患者血脂和血液流变学的影响。方法将100例颈动脉粥样硬化患者随机分为2组,治疗组50例予轻身降脂饮联合辛伐他汀片治疗,对照组予单纯辛伐他汀片治疗。2组治疗3个月后观察血脂和血液流变学变化。结果 2组治疗后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)较本组治疗前下降(P<0.01),高密度脂蛋白胆固醇(HDL-C)升高(P<0.01);治疗组治疗后TC、TG、LDL-C均低于对照组(P<0.05),HDL-C高于对照组(P<0.05)。2组治疗后全血黏度高切、全血黏度低切、血浆黏度、红细胞比容、纤维蛋白原均较本组治疗前降低(P<0.01);治疗组治疗后全血黏度高切、全血黏度低切、纤维蛋白原均低于对照组(P<0.05)。结论轻身降脂饮对颈动脉斑块患者血脂、血液流变学有明显改善作用。
Objective To investigate the effect of Qingshenjiangzhiyin on blood lipid and haemorheology in patients with atherosclerotic of carotid.Methods 100 patients with atherosclerotic of carotid were divided into two groups.Patients in treatment group （n=50） were treated by combination of Qingshenjiangzhiyin and Simvastatin tablet.50 cases in control group were treated by Simvastatin tablet.The changes of blood lipid and haemorheology were observed in two groups three months after treatment.Results TC,TG and LDL-C after treatment were decreased in comparison with those before treatment in two groups （P〈0.01）.HDL-C was increased （P〈0.01）.TC,TG and LDL-C in treatment group were decreased in comparison with those in control group after treatment （P〈0.05）.HDL-C in treatment group was increased after treatment （P〈0.05）.Haemorheology indexes including high shear viscosity,low shear viscosity,plasma viscosity,erythrocrit and fibrinogen after treatment were decreased in comparison with those before treatment in two groups （P〈0.01）.High shear viscosity,low shear viscosity and erythrocrit in treatment group were decreased in comparison with those in control group after treatment （P〈0.05）.Conclusion Qingshenjiangzhiyin can obviously improve blood lipid and haemorheology in patients with atherosclerotic of carotid.
出处
《河北中医》
2010年第7期974-976,共3页
Hebei Journal of Traditional Chinese Medicine
关键词
动脉硬化
降血脂药
颈动脉
超声检查
中西医结合疗法
Arteriosclerosis
Pharmacotherapy
Antihypercholesterolemic
Pharmacology
Carotid
Ultrasonograph
