摘要
目的观察电针结合饮食和运动疗法对胃肠实热型单纯性肥胖症的临床疗效,并探索其作用机制。方法采用随机对照的方法,分别设立针灸饮食运动组(治疗组)35例和饮食运动组(对照组)37例。观察两组临床疗效、主要症状疗效,治疗前后观察两组体质量、体质量指数(body mass index,BMI)、腰围的变化,检测治疗组治疗前后及健康对照者的空腹血糖(fasting blood sugar,FBS)、餐后2 h血糖(postprandial twohours plasma glucose,2hPG)、空腹胰岛素(fasting insulin,FINS)和餐后2 h空腹胰岛素(postprandial twohours fasting insulin,2hFINS)水平。结果治疗组临床总有效率显著高于对照组(P<0.01),多食易饥、畏热多汗、口干舌燥和大便秘结的总有效率显著高于对照组(P<0.05,或P<0.01);治疗组体质量、BMI及腰围下降值显著高于对照组(P<0.01);治疗组FINS及2hFINS水平较治疗前显著下降(P<0.01)。结论电针结合饮食运动疗法治疗胃肠实热型单纯性肥胖症疗效显著,并可同时改善其胰岛素抵抗状况。
Objective To investigate therapeutic effects of electroacupuncture ( EA ) combined with dietsand exercises in treatment of simple obesity complicated with excess heat syndrome of stomach and intestine, and explore the mechanism of treatment. Methods A total of 72 patients were randomized into treat- ment group and control group, 35 patients in treatment group were treated with EA combined with diets and exercises, while 37 patients in control group with diets and exercises. Total clinical effects and therapeutic effects of main symptoms were observed; before and after treatment, body mass, body mass index (BMI) and waistline of both groups were measured; levels of fasting blood sugar (FBS), fasting insulin (FINS), postprandial two hours fasting insulin (2hPG) and postprandial two hours fasting insulin (2hFINS) were assayed in treatment group before and after treatment, and FBS, FINS, 2hPG and 2hFINS were also assayed in healthy volunteers. Results Total effective rate in treatment group was significantly higher than that in control group (P〈0.01); and total effective rates of main symptoms such as eating many foods but feelinfg hungry, intolerance of heat and hyperhidrosis, dry mouth and tongue, and constipation were also significantly higher than those in control group (P〈0.01). Decrement values of body mass, BMI and waistline in treatment group were statistically higher than those in control group (P〈 0.01). The levels of FINS and 2hFINS of treatment group were significantly decreased compared with those before treatment (P〈0.01). Conclusion EA combined with diets and exercises has marked effects in treating simple obesity complicated with excess heat syndrome of stomach and intestine, meanwhile, it can improve insulin resistance.
出处
《安徽中医学院学报》
CAS
2010年第4期33-37,共5页
Journal of Anhui Traditional Chinese Medical College