摘要
目的探讨相差显微镜下血尿中红细胞形态改变在鉴别血尿来源中的临床价值。方法收集肾小球性疾病血尿215例;非肾小球性血尿233例;正常对照组210例,用相差显微镜观察尿红细胞形态与临床肾活检诊断血尿进行比较,评价相差显微镜下尿红细胞形态判定血尿来源的可靠性。结果215例肾小球性血尿患者中非均一红细胞血尿阳性率为96.3%,均一性红细胞血尿阳性率为3.7%,233例非肾小球性血尿患者中均一红细胞血尿阳性率为96.1%,非均一性红细胞血尿阳性率为3.9%。相差显微镜法的灵敏度为96.3%,特异度为96.1%。结论在相差显微镜下检测红细胞形态操作简便,结果与临床符合率较高,敏感性和特异性都较高,对鉴别血尿来源和定位诊断具有一定的临床应用价值。
Objective To explore the clinical significance of urinary red blood cell morphology in determining the source of hematuria.Methods Urines from 215 patients with glomerular hematuria,233 patients with non-glomerular hematuria were collected.Urines collected from 210 healthy subjects were used as control.Urine red blood cell morphology was observed under phase contrast microscope and hematuria was examined by renal biopsy.The reliability of urinary red blood cell morphology in determining of the source of hematuria was analyzed.Results In 215 patients with glomerularhematuria the positive rates of deformation red cells hematuria were 96.3%.Those of Homogeneous red cells hematuria were 3.7%;In 233 cases with non-blomerular hematuria the positive rates of the single red cells hematuria were96.1%,while deformation red cells hematuria were 3.9% the sensitivity of microscopy is 96.3% and specificity was 96.1%.Conclusion Morphology examination of urinary red blood cells with phase contrast microscope shows the diagnostic value in disclosing the source of hematuria.
出处
《临床和实验医学杂志》
2010年第18期1370-1372,共3页
Journal of Clinical and Experimental Medicine
关键词
血尿
相差显微镜
红细胞形态
Hematuria
Phase contrast microscope
Red blood cell morphology
