摘要
间日疟现症病人用复方蒿甲醚片，于治疗前及治疗后５、１２和２４ｈ分别以大劣按蚊叮咬吸血感染，结果用药前按蚊的唾腺子孢子阳性率为７５．８２％，用药后５ｈ有极少数吸血按蚊的胃壁卵囊阳性，但唾腺中均未检出子孢子。服药后患者血内疟原虫无性体及有性体较治疗前迅速减少，表明复方蒿甲醚能迅速杀灭红内期间日疟原虫，并能抑制其在蚊体内的孢子增殖。
Mosquitoes of An. dirus were allowed to bite a patient of vivax malaria before and 5 h, 12 h and
24 h after he was treated with artemether co. tablets. Breeding and dissection of the mosquitoes
showed that before treatment of artemether co., the sporozoite positive rate of An. dirus was 75.
82%. Few mosquitoes had oocyst in their guts and no sporozoite was found in their salivary
glands 5 h after treatment. Asexual and sexual parasites reduced rapidly in patients blood after
treatment. This indicated that artemether co. could kill P. vivax in erythrocytic phase and
restrain the sporozoite multiplication.
出处
《中国寄生虫病防治杂志》
CSCD
1999年第2期100-101,共2页
Chinese Journal of Parasitic Disease Control
关键词
复方蒿甲醚
间日疟
孢子增殖
疟疾
Artemether co., P. vivax, sporozoite
multiplication
