摘要
388例大肠腺瘤中93例伴有腺癌,癌变率为23.97％:腺瘤的不典型增生和癌变率随着年龄增长而增高,高峰年龄在60岁左右。绒毛状腺瘤(58.62％)比管状腺瘤(8.00％)有较高的恶变可能性。腺瘤的癌变率随着不典型增生严重程度递增而增高;重度(60.55％)比中度不典型增生(21.70％)有较高的恶变可能性。腺瘤恶变可能性与组织类型和瘤体大小等因素有关,而起主要作用的因素是不典型增生的程度。
The incidence of malignancy in 388 adenomas was about 23.97 per cent; the rate of both atypia and cancer in the adenomas sharply with increase in age,with a peak Incidence at sixty-years.The malignancy rate of tubular adenomas was low (8.00%), but much higher for villoug adenomas (58.62%), bhese results support bhe view that the villous type of growth has a higher malignant potential and the larger the adenoma the higher ds its malignant potential.The cancer rate in adenomas increases with the degree of epithelial atypia; severe atypia has a malignancy rate of about (60.55%), moderate atypia also shows a much higher mallnant potential (21.70%) than those with mild atypia (1.82%). Although hiBtological type and size of tumors are very important in the assessment of malignant potential, it seems that atypia has the paramount place.
出处
《上海医科大学学报》
CSCD
1990年第4期300-302,共3页
Journal of Fudan University(Medical Science)
关键词
大肠肿瘤
腺瘤
恶变
adenoma
atypia
malignant potential
