摘要
选择临床高度怀疑颅脑和椎管内占位病变,而常规磁共振成像(MRI)检查阴件者,或MRI检查所见,病变轮廓和范围不明确者,病灶与周围水肿不易区分者,及占位病变定性有困难者,共77例。作钆-二乙撑三胺五乙酸(Gd-DTPA)增强成像。注射Gd-DTPA后有助于①显示原来T_1和T_2加权图像都不能显示或显示不全的病灶,包括等信号病灶和小病灶,占本组病例的16.9％,其中9例得到肯定诊断;②更好地区别肿瘤和水肿组织;③协助区别良、恶性病变;④可省去T_2加权成像,故有利于节约时间。
Gadol.inium-diethylenetr famines pentaaoetio acid (Gd- DTPA) enhancement was selected for use in case a whose routine magnetic resonance imaging (MRI) were negative but were highly suspicious clinically for intra cranJal or intra spinal canal space-occupying lesions, and cages whose routine MRIs were positive but presented, difficulties in defining the contour or the character of the lesion, such as distinction of edama from the lesion. Altogether were 77 cases, in which 51 cases were Intra-cranial lesions and 26 cases intraspinal canal. For each patient Gd-DTPA 0.06-0.1 mmol. per kg. were injected intravenously 5 minutes before image aoquiaition (for pituitary micro-adenoma 1 minute before image acquisition). No patient developed contrast media reaction or complications. In cases with haemorrhage, hematoma, edema, cyst and arteriovenous malformation no remarkable enhancement was observed after the injection of contrast media. When difficulty in the differentia] diagnosis between these lesions and tumors occurs, injection of Gd-DTPA is very helpful. Gd-DTPA enhancement la of great benefit to the diagnosis of intraoranial or intraspinal canal tumors in the following four aspects: 1) to reveal lesions which can not be demonstrated or can not be demonstrated clearly, including isointensity lesions and small lesions. These comprised 16.9% of our cases, in 9 of these oases d iagnosis was equivocal but a definite dignosis was obtained after enhancement; 2) to differentiate the tumor tissue from edema more definitly; 3) is helpful in distinguishing benign legions form malignant lesions; 4) shortens the examination time due to omission of the T2 weighted image aquisition.
出处
《上海医科大学学报》
CSCD
1990年第1期31-34,共4页
Journal of Fudan University(Medical Science)
关键词
GD-DTPA
神经系统疾病
诊断
magnetic resonance imaging
gadolinium-diethy-lenetriamines pentaacetic acid
nervous system diseases
