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Duchenne肌营养不良患者的脊柱融合

Spinal fusion in Duchenne muscular dystrophy Walter B.Greene
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摘要 目的:观察肌营养不良患者脊柱固定融合术的疗效。方法:对1982~1995年接受脊柱融合的12例肌营养不良患者的病历和X线片进行回顾性研究。随访时间不少于1年。资料包括患者术前肺功能、手术步骤、随访时X线片Cobb角和骨盆倾斜程度及患者功能状态。结果:手术时患者年龄为135岁,术前肺功能为56%,脊柱侧凸平均48°,骨盆倾斜平均15°,所有患者均接受后路融合双鲁氏棒固定术和髂骨植骨。最后随访时没有发现不融合病例,脊柱侧凸平均31°,骨盆倾斜平均8°,所有患者均能够坐位而无不适。结论:后路融合双鲁氏棒固定术有助于维持肌营养不良患者的脊柱序列,建议对该类患者在脊柱侧凸发展至30°前行脊柱融合术。 Objective: To evaluate the result of spinal fusion in the patients with Duchenne muscular dystrophy(DMD). Method: Charts and radiographs were retrospectively reviewed on 12 patients with DMD who underwent spinal stabilization between 1982 and 1995.To be included in the age of the patient at operation,preoperative pulmonary function results,surgical procedure,and clinical status at final follow up. Result: The age at operation averaged 13.5 years,the preoperative forced vital capacity averaged 56%. All patients were treated with a posterior fusion and segmental fixation to dual Luque rods.Prior to operation,the scoliosis averaged 48,and was 31 at final follow up.Pelvic obiquity averaged 15 prior to operation and 8 at last follow up.No patient had a pseudoarthrosis.At last follow up,all patients were able to sit up all day without pain. Conclusion: posterior fusion and segmental fixation to dual Luque rods is an effective surgical procedure for the patients with DMD.If possible,spinal stabilzation
出处 《中国脊柱脊髓杂志》 CAS CSCD 1999年第3期132-135,共4页 Chinese Journal of Spine and Spinal Cord
关键词 肌营养不良 脊柱侧凸 融合 固定 治疗 Duchenne muscular dystrophy\ Scoliosis\ Spinal fusion\ Fixationin patients with DMD should be performed before the curvature is >30 degrees
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