期刊文献+

系统性硬皮病治疗的研究进展 被引量:7

暂未订购
导出
摘要 系统性硬皮病(SSc)是一种导致皮肤和内脏器官纤维化的自身免疫性疾病,以组织纤维化,闭塞性微血管病变,免疫异常为特点。对其治疗目前尚无特效的药物,除了围绕其发病机制展开外(抗纤维化药物、免疫抑制剂、血管活性药物),近年来对其并发症的有效治疗使该病的生存率大为提高。本文旨在概括以往治疗经验,着重介绍近年治疗研究进展。
作者 廉晓日 肖嵘
出处 《皮肤性病诊疗学杂志》 2010年第4期310-314,共5页 Journal of Diagnosis and Therapy on Dermato-venereology
  • 相关文献

参考文献29

  • 1Clements PJ,Furst DE,Wong WK,et al.High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis:analysis of a two-year,double-blind,randomized,controlled clinical trial[J].Arthritis Rheum,1999,42(6):1194-1203.
  • 2Derk CT,Huaman G,Jimenez SA.A retrospective randomly selected cohort study of D-penicillamine treatment in rapidly progressive diffuse cutaneous systemic sclerosis of recent onset[J].Br J Dermatol,2008,158(5):1063-1068.
  • 3Giordano N,Papakostas P,Lucani B,et al.Serum relaxin in systemic sclerosis[J].J Rheumatol,2005,32(11):2164-2166.
  • 4Seibold JR,Korn JH,Simms R,et al.Recombinant human relaxin in the treatment of scleroderma.A randomized,double-blind,placebo controlled trial[J].Ann Intern Med,2000,132(11):879-971.
  • 5Khanna D,Clements PJ,Furst DE.Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement:a randomized,double-blind,placebo-controlled trial[J].Arthritis Rheum,2009,60(4):1102-1111.
  • 6钱革,周武,吴剑波,周武庆,王千秋,禹卉千,李振鲁.氟伐他汀对系统性硬皮病成纤维细胞增殖及胶原分泌的影响[J].中国麻风皮肤病杂志,2009,25(9):645-647. 被引量:2
  • 7钱革,李建国,吴剑波,周武庆,王千秋,禹卉千,李振鲁.辛伐他汀对体外培养系统性硬皮病患者的成纤维细胞增殖和胶原表达的影响[J].中国皮肤性病学杂志,2009,23(8):478-480. 被引量:4
  • 8Krishna Sumanth M,Sharma VK,Khaitan BK,et al.Evaluation of oral methotrexate in the treatment of systemic sclerosis.Int J Dermatol 2007,46(2):218-223.
  • 9Miniati I,Matucci Cerinic M.Pulmonary fibrosis in systemic sclerosis:is treatment with cyclophosphamide more effective than placebo[J].Nat Clin Pract Rheumatol,2007,3(7):372-373.
  • 10Beretta L,Caronni M,Raimondi M,et al.Oral cyclophosphamide improves Pulmonary function in scleroderma patients with fibrosing alveolitis:experience in one centre[J].Clin Rheumatol,2007,26(2)168-172.

二级参考文献21

  • 1徐琳,李志梁,赵连友,刘映峰,李公信,丁明学,赵一俏,傅强,赵霞.辛伐他汀对鼠心脏成纤维细胞DNA合成的影响[J].南方医科大学学报,2006,26(2):205-207. 被引量:10
  • 2张彩香,李红,刘章锁.辛伐他汀抑制肾间质纤维化的实验研究[J].山西医药杂志,2006,35(4):286-288. 被引量:3
  • 3钱革,王千秋,张国成.他汀类药物在皮肤科的应用展望[J].国际皮肤性病学杂志,2006,32(3):139-141. 被引量:4
  • 4WATTS K L, SAMPSON E M, SCHULTZ G S,et al. Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts[J]. Am J Respir Cell Mol Biol,2005 ,32(4) :290 -300.
  • 5OHTSUKA T, KOIBUCHI N, SAKAI H, et al. Quantitative analysis of α1(Ⅰ)and α1(Ⅲ) procollagen mRNA expression in systemic sclerosis skin tissue-an in situ hybridization study [ J ]. Arch Dermatol Res, 1999, 291(11) :575 -582.
  • 6Furst DE,Clement PJ.Hypothesis for the pathogenesis of systemic sclerosis.J Rheumatol 1997;(suppl 48):53-57.
  • 7Marcellus DC,Altomonte VL,Farmer ER,et al.Etretinate therapy for refractory sclerodermatous chronic graft-versus-host disease[J].Blood,1999,93(1):66-70.
  • 8Masi AT,Rodnan GP,Medsger TA,et al.Preliminary criteria for the classification of systemic sclerosis (scleroderna)[J].Arthritis Rheum,1980,23(5):581-590.
  • 9Brennan P,Silman A,Black C,et al.Reliability of skin involvement measures in scleroderma.The UK Scleroderma Study Group[J].Br J Rheumatol,1992,31(7):457-460.
  • 10Binks M,Passweg JR,Furst D,et al.Phase Ⅰ/Ⅱ trial of autologous stem cell transplantation in systemic sclerosis:procedure related mortality and impact on skin disease[J].Ann Rheum Dis,2001,60(6):577-584.

共引文献12

同被引文献41

引证文献7

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部