摘要
目的探讨自动调节持续气道正压通气呼吸机(Auto-CPAP)与双水平正压通气呼吸机(Bi-PAP)在治疗重度阻塞性睡眠呼吸暂停综合征(OSAHS)患者时的疗效。方法 120例重度(AHI>40)OSAHS患者根据AHI是否大于60,并且夜间平均血氧饱和度(MSaO2)是否低于80%分为A组和B组,先后接受Auto-CPAP和Bi-PAP治疗,观察治疗前和治疗时PSG参数变化。结果 A组患者应用Auto-CPAP较Bi-PAP治疗效果无明显差异,B组患者应用Bi-PAP较Auto-CPAP治疗效果明显改善。治疗效果主要表现在睡眠效率(SE),觉醒次数(WASO),Ⅰ期+Ⅱ期,Ⅲ期+IV期及REM期睡眠各占总睡眠时间(TST)的比例,而呼吸暂停低通气指数(AHI),夜间平均血氧饱和度(MSaO2),夜间最低血氧饱和度(LSaO2)无明显差异。结论对于重度OSAHS患者,AHI≤60,MSaO2≥80%的患者建议选择Auto-CPAP进行治疗,AHI大于60,MSaO2低于80%建议选择Bi-PAP进行治疗。
Objective To explore the application of auto-positive airway pressure （ Auto-CPAP ） and bi-level positive airway pressure （ Bi-PAP） on the patients with severe obstructive sleep apnea-hypopnea syndrome （ OS-AHS）. Methods 120 OSAHS patients were divided into two groups,namely 60 with AHI≤60 and M SaO2≥80% in A group and 60 with AHI〉 60 and M SaO2〈 80% in B group. All patients received Auto-CPAP one day and Bi-PAP therapy the next day. The changes of PSG parameters were observed. Results The therapy effects of Auto-CPAP and Bi-PAP in A group has no significance. The therapy effects of Bi-PAP were much better than Auto-CPAP in B group. The effects of treatment were manifested as sleep efficiency （ SE） ,number of WASO （ wake after sleep onset） ,time of NREM I ＋ II over total sleep time,time of III ＋ IV and REM over total sleep time. The apnea-hypopnea index （ AHI） ,night time mean SaO2（ M SaO2） and nighttime the lowest SaO2 （ L SaO2） have no significance. Con-clusion For severe OSAHS patients,when AHI≤60 and M SaO2≥80% ,Auto-CPAP should be used,and when AHI 〉60 and M SaO2 〈80% ,Bi-PAP should be selected for therapy.
出处
《中国临床保健杂志》
CAS
2010年第4期354-356,共3页
Chinese Journal of Clinical Healthcare
