摘要
目的观察双歧三联活菌与马来酸曲美布汀联合治疗腹泻型肠易激综合征的疗效。方法将75例腹泻型肠易激综合征患者随机分成两组,即治疗组38例,口服马来酸曲美布汀片0.2g,tid,联用双歧三联活菌胶囊(培菲康)40mg,bid,疗程2周;对照组37例,单用马来酸曲美布汀片,用法同联合治疗组。分别比较两组治疗前后临床症状,并在治疗结束时进行临床疗效评价。结果治疗组疗效较对照组有明显改善,治疗组总有效率为92.11%;对照组总有效率为81.08%,两组比较差异有显著性(P<0.05)。治疗组用药后症状明显较本组治疗前改善,与对照组治疗后比较,差异有显著性(P<0.05)。结论双歧三联活菌与马来酸曲美布汀联合治疗腹泻型肠易激综合征疗效满意。
Objective To investigate the curative effect of bifid triple viable bacteria capsules combined with trimebutine maleate tablets on the treatment of diarrhea irritable bowel syndrome. Methods 75 patients with diarrhea irritable bowel syndrome were divided into two groups： 38 patients of treatment group treated with trimebutine maleate tablets,0. 2 g,tid, po and bifid triple viable bacteria tablets,40 mg,bid,po,37 patients of control group treated with trimebutine maleate tablets in the same therapeutic way. The clinical symptom of two groups was compared before and after treatment,respectively,and clinical efficacy was evaluated after treatment. Results The symptoms of treatment group were significantly improved than the control group. The total effective rate of it （ 92. 11% ） was higher than that of the control （ 81. 08% ） ,P 0. 05. Conclusion The treatment of bifid triple viable bacteria tablets combined with trimebutine maleate tablets can provide a satisfactory effect for patients with diarrhea irritable bowel syndrome.
出处
《医药导报》
CAS
2010年第8期1013-1015,共3页
Herald of Medicine
关键词
双歧三联活菌
曲美布汀
马来酸
综合征
肠易激
腹泻
Bifid triple viable bacteria
Trimebutine maleate
Irritable bowel syndrome
Diarrhea
