摘要
目的:探讨米索前列醇预防产后出血的临床效果。方法:选择252例足月分娩产妇,将其随机分为观察组和对照组各126例,在胎儿肩娩出后分别采用米索前列醇口服和缩宫素肌注治疗。观察两组的临床效果及药物副反应。结果:观察组第三产程时间、产后2h出血量及产后出血发生率均明显少于对照组(P<0.01或P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:米索前列醇预防产后出血的效果优于缩宫素,值得临床推广应用。
Objective：To explore the clinical effect of misoprostrol in preventing postpartum hemorrhage. Methods：252 parturients were randomly divided into observation group and control group,received treatment of orally misoprostrol and intramuscularly oxytocin respectively. The clinical effect and side effects were observed in two groups. Results：Comparison of the duration of third birth process and bleeding dosage of 2 hours after postpartum and incidence of postpartum hemorrhage,the observation group were significantly smaller than those of control group （P〈0.01 or P〈0.05）. There were no significant difference in two groups as compared incidence of side reaction. Conclusion：The therapeutic effects of misoprostrol in preventing postpartum hemorrhage is significantly superior to oxytocin,and it can be widely used in clinic.
出处
《中国当代医药》
2010年第23期61-62,共2页
China Modern Medicine
关键词
米索前列醇
产后出血
缩宫素
Misoprostrol
Postpartum hemorrhage
Oxytocin
