沙美特罗替卡松粉吸入剂治疗哮喘的临床疗效分析被引量：9

Therapeutic effect of salmeterol xinafoate and fluticasone propionate powder for inhalation on asthma

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摘要目的:观察吸入沙美特罗替卡松粉治疗成人哮喘的临床疗效。方法:将80例哮喘患者分为治疗组与对照组,治疗组给予沙美特罗替卡松粉吸入治疗,对照组给予布地奈德粉吸入剂治疗。观察患者治疗前后临床症状及肺功能[用力呼气肺活量(FVC),第1秒用力呼气容积率(FEV1%)和用力呼气峰流速(PEFR)]的变化。结果:与治疗前比较,两组患者治疗后临床症状、肺功能各项指标、血清IL-4和IgE水平均得到明显改善;治疗后治疗组临床疗效、肺功能FVC、FEV1%和PEFR均明显优于对照组,但两者血清IL-4和IgE水平差异无统计学意义。结论:沙美特罗替卡松粉吸入剂治疗成人哮喘疗效显著,适于临床应用。 Objective：To observe the effect of salmeterol xinafoate and fluticasone propionate powder for inhalation in the treatment of adults with asthma. Methods：80 cases with asthmatic were randomly divided into trial group and control group. The trial group received salmeterol xinafoate and fluticasone propionate powder for inhalation,the control group received budesonide powder for inhalation at the same time.The clinical symptom and pulmonic function[forced vital capacity （FVC）,forced expiratory volume in one second（FEV1%） and peak expiratory flow rate（PEFR）] were observed before and after treatment respectively. Results：The clinical symptom,pulmonic function,serum IL-4 and IgE level of bronclial asthma patients were improved significantly after treatment; The clinical symptom and the values of FVC,FEV1% and PEFR in trial group were better than those of the control group after treatment,but the serum IL-4 and IgE level had no significant difference. Conclusion：Salmeterol xinafoate and fluticasone propionate powder for inhalation has better clinical curative effect in asthma,it is fit for clinical application.

作者彭国庆周永英

机构地区湖南省岳阳市二人民医院药剂科

出处《中国当代医药》 2010年第23期59-60,62,共3页 China Modern Medicine

关键词沙美特罗替卡松粉吸入剂哮喘布地奈德粉吸入剂 Salmeterol xinafoate and fluticasone propionate powder for inhalation Asthma Budesonide powder for inhalation

分类号 R974 [医药卫生—药品]

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