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丽珠肠乐治疗早期新生儿高胆红素血症的临床效果观察

A cliucal observation of treatment with bifdobiogen in early neonatal hyperbilirubinemia
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摘要 目的比较丽珠肠乐(双歧杆菌活菌制剂)与酶诱导剂(鲁米那、尼可刹米)在治疗早期新生儿高胆红素血症的临床疗效。方法将92例早期新生儿高胆红素血症的病人随机分为治疗组49例.以丽珠肠乐(双歧杆菌活菌制剂350mg/d)配以蓝光照射治疗,对照组43例以酶诱导剂鲁米那5mg/(kg·d),尼可刹米100mg/(kg·d)并配以蓝光照射,总疗程5夭。结果治疗组显效率(77.6%)高于对照组(44.2%),P<0.01。结论双歧杆菌活菌制剂治疗早期新生儿高胆红素血症优于酶诱导剂。 Objective To compare the effects of bifidobiogen with enzyme inductor(luminal, nikethamidum) in treatment early neonatal hyperbilirubinemia. Methods 92 babies with early neonatal hyperbilirubinemia were divided into 2 groups, randomly. 49 patients were treated with bifidobiogen 350 mg/(kg. d) and phototherapy. Other 43 patients were treated with enzyme lnductor luminal 5mg/(kg. d) ; nikethamidum 100mg/(kg. d)and phototherapy as the control group. Results The total effective rate in the treatment gr0up(77. 6% ) was higher than that in the control group (44. 2% ), P<0. 01. Conclusion Bifidobiogen is superior to enzyme inductor in treating early neonatal hyperbilirubinemia.
作者 薛芳菁 杨媛
出处 《中国综合临床》 1999年第2期168-169,共2页 Clinical Medicine of China
关键词 高胆红素血症 药物疗法 丽珠肠乐 新生儿 Neonatal hyperbilirubinemia Bifidobiogen Enzyme inductor
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