摘要
目的探讨老年女性急性心肌梗死患者发病情况及近期死亡的影响因素。方法选择初发急性ST段抬高心肌梗死后收治入院的女性患者共336例,根据年龄分为2组:老年组298例,非老年组38例。回顾性分析比较2组患者一般临床资料、发病特点和发病后30d内死亡情况,采用多元logistic回归分析年龄对女性急性心肌梗死患者近期死亡的影响。结果老年组患者年龄、血肌酐明显高于非老年组患者,而左心室射血分数明显低于非老年组患者,差异有统计学意义(P<0.05,P<0.01);老年组患者近期病死率明显高于非老年组患者(25.8% vs5.3%,P<0.01)。年龄≥60岁的女性是急性心肌梗死后30d死亡的独立危险因素,其死亡危险较非老年组患者高6.6倍(OR=6.553,95% CI:1.183～36.294,P<0.01)。结论老年女性急性心肌梗死患者具有更高的近期病死率。年龄≥60岁、发病至入院时间、空腹血糖、严重心律失常和急性左心功能不全是预测女性急性心肌梗死患者近期死亡的独立预测因素。
Objective To investigate the morbidity and inhospital fatality of female patients with initial acute myocardial infarction and to analyse the influential factors.Methods Three hundred and thirty-six inhospital female patients with acute myocardial infarction were enrolled into this cohort study.According to whether the age was above 60 yrs,the patients were divided into two groups and the patient’s outcomes were recorded during the hospital stay.At the end of study,a logistic regression analysis was conducted to reveal the effect of age（≥60 yrs） on fatality of female patients with acute myocardial infarction.Results The elder female patients（≥60 yrs） with acute myocardial infarction had a higher 30day fatality than the younger ones（25.8% vs 5.3%,P〈0.01）.The elder group had a higher serum creatinine level and lower left ventricular ejection fraction.The logistic regression analysis indicated that the elder female patients had a higher risk of death by 6.6 times than the younger group（OR=6.553,95%CI：1.183-36.294,P〈0.01）.Conclusion The elder female patients with acute myocardial infarction have a higher inhospital fatality.The age,time from disease onset to treatment,blood sugar level,arrhythmia and acute heart failure are independent predictors of female patients’ death after onset of acute myocardial infarction.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2010年第8期701-704,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
北京市自然科学基金(7072032)
关键词
心肌梗死
死亡
每搏输出量
危险因素
回顾性研究
myocardial infarction
death
stroke volume
risk factors
retrospective studies
