摘要
目的:了解我院抗菌药致药品不良反应(ADR)发生情况,为临床安全用药提供参考。方法:对我院2007～2009年上报的抗菌药401例ADR进行回顾性分析。结果:401例ADR报告中共涉及33种抗菌药,其中喹诺酮类药引起的ADR最多(25.94%),其次为头孢菌素类(24.69%);以静脉滴注给药途径引起的ADR最常见(78.05%);ADR临床表现以皮肤及其附件损害最多见(49.27%)。结论:应加强抗菌药ADR监测工作,保障患者用药安全。
Objective ： To investigate the status and characteristics of adverse drug reactions （ADRs） of antibacterial drugs occurring in our hospital for reference of rational use of antibacterial drugs. Methods-401 ADR cases reported in our hospital from Jan. 2007 to Dec. 2009 in our hospital were classified and analyzed. Results： A total of 33 kinds of antibacterial drugs were involved in ADR events, and quinolones dominated the first place （25.94%） and were followed by cephalosporins（24.69% ）. 313 ADRs （78.05%） were induced by intravenous route. The major systems involved were skin and its appendages（49.27% ）. Conclusion：It is important to intensify ADR monitoring of antibacterial drugs and ensure patients＇ medication safety.
出处
《药物流行病学杂志》
CAS
2010年第8期433-434,共2页
Chinese Journal of Pharmacoepidemiology
关键词
药物不良反应
抗菌药
合理用药
Adverse drug reactions
Antibacterial drugs
Rational use of drugs
