摘要
建立了用HPLC测定烧烫灵软膏中磺胺醋酰钠和磺胺含量的方法。在SpherisorbC18柱上，以V（甲醇）：V（体积分数为0．25％的醋酸溶液）=7：93为流动相，于257nm波长处检测。平均回收率：砍胶醋酰钠为98．9％（n=5），RSD=0．64％；磺胺为99．3％（n=5），RSD=1．58％。方法简便、快速、准确、重现性好。
An HPLC method for the determination of sulfacetamide sodium and sulfanilamide in Shao Tang Ling ointment was developed. The chromatographic conditions were: column, Spherisorb C18, mobile phase,methanol-0. 25% (V/V)-acetic acid solution (7: 93) ; detector UV-257 nm. The average recoveries were 98.9% (n= 5), RSD= 0. 64% for sulfacetamide sodium and 99. 3 % (n = 5), RSD= 1. 58% for sulfanilamide.The analytical method is simple, quick, accurate and reproducible.
出处
《色谱》
CAS
CSCD
北大核心
1999年第2期206-207,共2页
Chinese Journal of Chromatography
关键词
烧烫灵软膏
磺胺醋酰钠
磺胺
测定
HPLC
high performance liquid chromatography, Shao Tang Ling ointment, sulfacetamide sodium,sulfanilamide
