2Opp MR. Sleep and [J]. Immunol Allergy Clin North Am, 2009, 29(2): 295-307.
3Dantzer R, O'Connor JC, Freund GG, et al. From inflammation to sickness and depression: when the immune system subjugates the brain[J]. Nat Rev Neurosci, 2008, 9(1): 46-56.
4Opp MR. Cytokines and sleep[J]. Sleep Med Rev, 2005, 9(5) : 355- 364.
5Krueger JM, Obdl F Jr, Fang J. Humoral regulation of physiological sleep: cytokines and GHRH[J]. J Sleep Res, 1999, 8(Suppl 1) : 53- 59.
6Breder CD, Dinarello CA, Saper CB. Interleukin-1 immunoreactive innervation of the human hypothalarnus[J]. Science, 1988, 240 (4850) : 321-324.
7Breder CD, Tsujimoto M, Terano Y, etal. Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivlty in the murine central nervous system[J]. J Comp Neurol, 1993, 337(4): 543 567.
8Ban EM. Interleukin 1 receptors in the brain: characterization by quantitative in situ autoradiography[J]. lrnmunomethods, 1994, 5 (1) : 31-40.
9Krueger JM, Walter J, Dinarello CA, etal. Sleep-promoting effects of endogenous pyrogen (interleukin-1) [J].Am J Physiol, 1984, 246 (6 Pt 2) : R994-R999.
10Kubota T, Li N, Guan Z, et al. Intrapreoptic microinjection of TNF- alpha enhances non REM sleep in rats[J]. Brain Res, 2002, 932(1 2) : 37-44.
3Greene R, Siegel J. Sleep: a functional enigma. Neuromolecular Med, 2004, 5(1):59
4Schussler P, Uhr M, Ising M, et aL Nocturnal ghrelin, ACTH, GH and eortisol secretion after sleep deprivation in humans. Psychoneuroendoerinology, 2006, 31(8):915
5Vgontzas AN, Mastorak, os G, Bixler EO, et aL Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications. Clin Endocrinol(Oxf), 1999, 51(2) :205
6Vgontzas AN, Zoumakis E, Bixler EO, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J CAin Endocrinol Metab, 2004, 89(5):2119
4Zhang Y, Diao YP, You XM, et al. Quality assessment of Zaoren an shen granule by ttigh- perlbrmance liquid ehvomatography fingerprinting and quantitative analysis[J ]. J Med Plant Res,2010,4(16) : 1 628 - 1 636.
5Lyre C, Ping TS, Wang MF, et al. Brain distribution of cytokine mRNA in- duced by systemic administration of interleukin - 1 β or tumor necrosis factot α[J]. Brain Res ,2006, 1 120(1 ) :64 - 73.