摘要
目的:考察注射用还原型谷胱甘肽和肌苷葡萄糖注射液的配伍稳定性。方法:采用紫外分光光度法,测定室温(25℃)条件下6 h内配伍液中2组分的含量变化,并比较配伍前后外观、pH的变化。结果:配伍6 h内肌苷含量无明显变化,还原型谷胱甘肽的含量却下降至原来的41.1%。其余考察指标无显著性变化。结论:注射用还原型谷胱甘肽与肌苷葡萄糖注射液可以配伍使用,但应在2 h内用完。
Objective： To study the compatibility of reduced glutathione for injection and inosine glucose injection. Method： The contents of 2 constituents of the mixed solution stored at 25 ℃ within 6 hours was determined by ultraviolet wavelength spectrophotometry, and the appearance, pH value of the mixture were compared with those before. Result： There was no significant change in the content of inosine after mixing for 6 h ,while the content of reduced glutathione down to the original 41.1% at 6 h, no significant changes were noted otherwise. Conclusion： Reduced glutathione for injection is compatible with Inosine glucose injection if at 25℃ within 2 hours＇ mixing.
出处
《中国药师》
CAS
2010年第8期1149-1150,共2页
China Pharmacist
基金
哈医大二院青年基金(编号:QN2009-04)
