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血清胱抑素C对ICU危重患者急性肾损伤的诊断价值 被引量：7

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摘要 目的探讨血清胱抑素C(Scys C)对早期预测和诊断ICU危重患者急性肾损伤(AKI)的价值。方法ICU患者113例,分为AKI组37例和非AKI组76例。分别检测两组Scys C、血清肌酐(Scr)、估计肾小球滤过率(eGFR),并比较两组患者上述指标的差异。结果AKI患者的Scys C和Scr水平均较非AKI患者显著升高(P均<0.05);AKI患者的Scys C与Scr呈正相关(r=0.613,P<0.01),(Scys C)-1与eGFR呈正相关(r=0.814,P<0.01)。AKI患者的Scys C水平早于Scr出现异常,Scys C诊断AKI的灵敏度明显优于Scr(P<0.05)。结论ScysC能较Scr更敏感、准确地反映危重患者早期肾功能的损害。
作者 于志勇 董明华 宋丽艳
机构地区 烟台市莱阳中心医院
出处 《山东医药》 CAS 北大核心 2010年第29期32-33,共2页 Shandong Medical Journal
关键词 肾损伤 急性 胱抑素C 肌酐 肾小球滤过率
分类号 R692.5 [医药卫生—泌尿科学]
  • 相关文献

参考文献8

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二级参考文献11

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共引文献38

同被引文献55

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引证文献7

二级引证文献17

山东医药
2010年 第29期

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