摘要
目的探讨慢性乙型肝炎(CHB)面部五色诊断与临床病理之间的相关性。方法选择临床诊断为轻、中、重度慢性乙型肝炎以及乙肝肝硬化的患者,在日常光线下,采用Canon Power Shot G5数码相机拍摄患者面部照片,根据色调、色泽对比初步确立面色分级,并行肝穿刺病理组织活检确立病理炎症分级和纤维化分期。结果经SPSS11.0统计学相关性分析,慢性乙型肝炎面部五色变化(包括颜色和光泽度)与病理炎症分级、纤维化分期之间存在等级正相关关系。结论慢性乙型肝炎轻度、中度、重度以及早期肝硬化患者面部五色诊与肝脏病理炎症和纤维化程度之间存在正相关性,即随着炎症程度的加重,或者纤维化程度的进展,相应的会出现面色善恶变化的趋势。这一结论可以用于指导临床中西医结合诊断和治疗。
Objective To observe the correlation between traditional Chinese medical diagnosis of five complexions and liver biopsy of patients with chronic Hepatitis B （CHB）. To study the principles of diagnosis of five complexions and broaden our treatments based on differential diagnosis. Methods Seventy-three patients with mild or moderate CHB were diagnosed in the department of traditional Chinese medicine （TCM） of the third affiliated hospital of Sun -Yet-san University. All enrolled cases accorded with ＂the diagnostic standard of virus hepatitis＂ which was jointly revised by the Chinese Society of Infectious Diseases and Parasitology. The schedule table was made according to the principles of Chinese four diagnostic methods and then establishment of differential diagnosis by two traditional Chinese physicians. At the same time, histological evaluation has been conduct by two independent pathologists. Statistical analysis was performed using the SPSS 11.0 software. The P values less than 0.05 （2-tailed） were considered to indicate significance. Results There is a direct correlation between five complexions and the inflammation class and fibrosis staging of liver biopsy of CHB. Conclusions There is direct correlation between five complexions of face and liver biopsy in CHB and early cirrhosis. The tendency from favorable complexion to unfavorable complexion is directly correlative to inflammation and fibrosis.
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2007年第2期86-89,共4页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
基金
广东省中医药管理局科研课题(100115)
关键词
中西医结合
慢性乙型肝炎
肝脏病理
Combination of TCM with western medicine Chronic hepatitis B Liver biopsy
