摘要
目的探讨实时三维超声心动图(RT-3DE)左心室重构指数(LVRI)、整体峰值充盈率/射血率(gPFR/gPER)、左心室射血分数(LVEF)评价冠状动脉搭桥术(CABG)效果。方法采集CABG组术前3d、术后1周、术后1个月3个时间点和正常对照组各研究对象的左心室全容积图像。在分析软件上得到gPFR、gPER和LVEF,并计算LVRI。比较各参数在CABG组与正常对照组CABG手术前后的差异,以及各组在各时间点内的相关性。结果 CABG各组的各参数均较正常对照组减低(P<0.01);CABG术后1周各参数与术前相比差异无统计学意义(P>0.05);术后1个月各参数较术前与术后1周增高(P<0.01)。相关性分析表明:gPER与LVEF、gPFR在各组各时间点内均有显著相关性(r=0.805～0.983,P均<0.01);LVRI与LVEF、gPER、gPFR在CABG各组均有显著相关性(r=0.705～0.928,P均<0.01),但在正常对照组内均无显著相关性(r=0.096～0.134,P均>0.05)。结论来源于RT-3DE的LVRI、gPER、gPFR、LVEF能综合评价CABG手术的效果。
Objective To evaluate the effect of coronary artery bypass grafting （CABG） by real- time three-dimensional eehocardiographic （RT-3 DE） left ventricular remodeling index （LVRI）, global peak filling/ejection rate（ gPFR / gPER） and left ventricular ejection fraction（LVEF）. Methods RT-3DE full volumetric dataset of 22 healthy subjects （normal controls group） and 30 patients of CABG （ including group of pre-CABG, the group of one week after CABG and the group of one month after CABG） were enrolled. The gPFR, gPER and LVEF in all subjects were offline obtained by 4D left ventricular analysis CAP 2.5 software from TomTec company; The LVRI were calculated. Then the differences of all parameters between normal controls group and CABG subgroups, between pre-CABG subgroup and one week / one month after CABG subgroups; the correlations between LVRI and gPER/LVEF/gPFR, gPER and gPFR/LVEF in all groups were compared. Results All parameters of CABG subgroups were significantly lower than those of normal controls group （ P 〈 0.05 ） ; all parameters of one month after CABG subgroup were significantly greater than those of pre-CABG subgroup/one week after CABG subgroup（ P 〈 0.05 ） ; but all parameters of one week after CABG subgroup were comparable with those of pre-CABG subgroup （ P 〉 0. 05 ）. Correlation analysis indicated that good positive correlations between gPER and gPFR/LVEF in all groups （ r = 0. 805 0. 983, all P 〈0. 01 ） ; good positive correlations between LVRI and gPER/LVEF/gPFR in CABG subgroups were observed（r = 0. 705 - 0. 928, all P 〈 0.01 ）, but no good positive correlations between LVRI and gPER/LVEF/gPFR in normal controls group （ r = 0. 096 - 0. 134, all P 〉 0.05 ） were found, respectively. Conclusions The LVRI, gPER, LVEF, gPFR derived from RT-3DE can assess the effects of CABG.
出处
《中华医学超声杂志（电子版）》
2010年第8期21-24,共4页
Chinese Journal of Medical Ultrasound(Electronic Edition)
关键词
三维超声心动描记术
心室重构
心室功能
冠状动脉搭桥术
Three-dimensional echoeardiography
Ventricular remodeling
Ventricular function
Coronary artery bypass grafting
