摘要
目的：为了评价生长抑素对急性胰腺炎的疗效。方法：４８例确诊为急性胰腺炎患者随机分为：对照组２５例，给予常规治疗；治疗组２３例，在常规治疗基础上加用生长抑素２５０μｇ／ｈ持续静脉滴注，疗程３～１４ｄ。结果：治疗组腹痛缓解时间明显快于对照组，其差异有非常显著意义（Ｐ＜０００１）；重要实验室指标血白细胞，淀粉酶、乳酸脱氢酶治疗组降低幅度大于对照组，其差异有显著性（Ｐ＜００５）；治疗组并发症发生率少于对照组，但无统计学意义。结论：生长抑素可明显缓解急性胰腺炎患者腹痛症状，并有阻止病情严重化，减少并发症之趋势。
Aim: To evaluate the efficacy of somatostatin in the treatment of acute pancreatitis.Methods: Forty eight patients were randomized to control group ( n =25), received ordinary therapy, somatostatin group ( n =23), received ordinary therapy plus infusion of somatostatin 250 μg/h.Results: The time to obtain relief of abdominal pain in the somatostatin group was less than control group significantly( P <0 001),laboratory tests compared in the somatostatin group( P <0 05) a drop in serum amylase,LDH concentrations and WBC were significantly larger.The incidence of complications were lower in the somatostatin group, however the difference was not statistically significant.Conclusions: Somatostatin was efficacious for relieving the abdominal pain and may reduce the severity of acute pancreatitis.
出处
《暨南大学学报（自然科学与医学版）》
CAS
CSCD
1999年第2期50-52,共3页
Journal of Jinan University(Natural Science & Medicine Edition)
