摘要
【目的】探讨影响子宫内膜腺鳞癌临床预后的因素。【方法】回顾性研究51例子宫内膜腺鳞癌患者的临床资料。【结果】①腺鳞癌占同期全部宫内膜癌的4.78%(51/1066),腹膜后淋巴结转移率为14.0%(6/43)。⑦肌层浸润〈1/2与〉1/2的官外转移率分别为26%(6/26)和62.5%(10/16),两者相比较差异具有显著性(P〈0.05)。③腺癌分化程度与浸润肌层深度有关(P=0.035)。④Ⅰ和Ⅱ期5年生存率86.7%(26/30),Ⅲ期5年生存率63.6%(7/11),而Ⅳ期2年生存率为28.6%(2/7)。【结论】子宫内膜腺鳞癌临床特征与普通子宫内膜样腺癌无明显区别。分化程度和肌层浸润深度是影响其预后的重要因素。
[Objective]To explore the influential factors of clinical characteristics and prognosis of adenosquamous carcinoma of the endometrium. [Methods]The clinical data of 51 cases with adenosquamous carcinoma of the endometrium confirmed by pathology were retrospectively analyzed. [Results]Among 1066 endometrial cancer patients, 51 patients(4.78%) were adenosquamous carcinoma of the endometrium. The retroperitoneal lymph node metastasis rate was 14.0%(6/43). Extra-uterine metastasis rate of patients with muscular infihration〈1/2 and 〉 1/2 were 26% (6/26) and 62. 5 % (10/16), respectively, and there was significant difference between them( P 〈0. 05). The path-ologic grade of ad was correlated with the depth of muscular infiltration( P = 0. 035). The 5-year overall survival rate was 86.7%(26/30) in stage Ⅰ and Ⅱ, and 63.6% (7/11) in stage Ⅲ, while the 2-year overall survival rate was 28.6%(2/7) in stage Ⅳ. [Conclusion]The clinical characteristics and prognosis of adenosquamous carcinoma of the endometrium are similar to common endometrioid adenocarcinoma cular infiltration are important factors which affect the prognosis.
出处
《医学临床研究》
CAS
2010年第7期1234-1236,共3页
Journal of Clinical Research
关键词
癌
鳞状细胞
子宫内膜肿瘤
预后
carcinoma,squamous cell
endometrial neoplasms
The pathologic grade and depth of mus prognosis