摘要
目的对上海市１９８７年～１９９６年鉴定的５６１９株分支杆菌菌种鉴定结果进行分析，对其中非结核分支杆菌耐药性测定结果进行探讨。方法全部菌株的鉴定按１９８４年全国结核病细菌学检验规程进行。结果人型５４６５株（９７３％）、牛型２２株（０４％）、非结核分支杆菌１３２株（２３％），其中偶发４２株、胞内３０株、龟型１７株、瘰疬１０株、堪萨斯９株、戈登９株、浅黄６株、草分支４株、不产色２株、金色２株、溃疡１株。非结核分支杆菌（ＭＯＴＴ）对ＰＡＳ、ＩＮＨ、ＳＭ、ＲＦＰ、ＥＭＢ与ＫＭ的耐药率分别为７２４％、６１２％、４９０％、４３９％、３１６％和２７６％。对１～６种药物的耐药率分别为１３３％、２１４％、２４５％、１６３％、１０２％和６１％。结论上海市肺结核患者感染菌种主要为人型结核分支杆菌（９７３％），而牛型（０４％）和非结核分支杆菌（ＭＯＴＴ，２３％）所占比重很小，明显低于全国水平。
Objective To analysis of the identification of Mycobacterium species in strains and drug resistance of Mycobacterium other than Tuberculosis(MOTT) during The periol 1987～1996 in Shanghai.Methods The specific identification of Mycobacteriam and drug susceptibility test were conducted with traditional methods.Results The strains of M.tuberculosis,M.bovis and M.nontuberculosis were 5465(97.3%),22(0.4%),and 132(2.3%)respectively.There were 42 strains of M.tortuitum,30 of M.intrcellulare,17 of M.chelonae subsp,10 of M.scrofulaceum,9 of M.kansnsii,9 of M.gordonae,6 of M.gilvum,4 of M.phlei,2 of M.nonchromogenicum,2 of M.aurum and 1 of M.ulcerans respectively in total of 132 M.nontuberculosis.The rate of resistance to PAS was 72.4%,to INH 61.2%,to SM 49.0%,to RFP 43.9%,to EMB 31.6% and to KM 27.6%.The rate of resistance to only one agent was 13.3%,to two 21.4%,to three 24.5%,to four 16.3%,to five 10.2% and to six 6.1% respectively.Conclusion The pulmonary tuberculosis cases in Shanghai were infected mainly with M.tuberculosis(97.3%)and infected by MOTT only 2.3%,but the high resistance rate of MOTT should be pay great attention.
出处
《中国防痨杂志》
CAS
1999年第1期34-36,共3页
Chinese Journal of Antituberculosis
关键词
分枝杆菌
菌种
鉴定
肺结核
Mycobacterium Specific identification
