摘要
探讨椎基底动脉短暂缺血性发作（ＶＢＴＩＡ）的发病机理。方法患者组６５例，对照组２６例，作磁共振血管成像（ＭＲＡ）和经颅多普勒（ＴＣＤ）检查。测量ＶＢＴＩＡ的脑血流量（ＣＢＦ）。结果对照组双侧椎动脉（ＶＡ）ＣＢＦ为１１２．３～２７８．９ｍｌ／ｍｉｎ（均值１９５．６），较患者组４８．０～２６２．０ｍｌ／ｍｉｎ（均值１４．９０）高（Ｐ＜０．０１）。１５例患者ＣＢＦ降低，双侧ＶＡ广泛迂曲者下降明显，均值为１０７．５ｍｌ／ｍｉｎ，ＶＡ重、中、轻度狭窄或发育不良者均值分别为１２０．０、１４１．３、１５４．２（ｍｌ／ｍｉｎ）。三者健侧ＣＢＦ占双侧ＣＢＦ的百分比分别为９１．５％、８２．０％、６５．８％。结论通过ＭＲＡ和ＴＣＤ可以测量ＣＢＦ，它是诊断ＶＢＴＩＡ的量化指标，对诊断ＶＢＴＩＡ和认识其发病机理具有重要意义。
Objective To measure the cerebral blood flow (CBF) volume of the patients with vertebro-basilar transient ischemic attack (VBTIA),and to investigate the pathogenesis of VBTIA. Methods 65 patients group and 26 control group were examined by MRA and TCD. Results CBF volumeof 112.3～278. 9ml/min in control group with mean 195.6 of CBF was higher than that of 48.0～262.0ml/min in patients group with mean 149 of CBF (t=2. 43,P<0. 01). In the patients group, CBF volume of 15 patients were low, CBF volume in patients with diffuse twist of bilateral extracranial VA wasthe lowest, with the mean CBF of 107.5ml/min,in patients with severe,mediate and mild stenosis or hypoplasia of unilateral VA, the mean CBF volume were 120.0, 143.3 and 154.2 (ml/min) respectively,percentages of CBF volume of another lateral VA in total CBF volume of both VA were 95.1%,82.0%and 65.8% respectively. Conclusion With the combination of MRA and TCD, the CBF volume of bilateral VA can be measured, it is guantitative, and is important sigificance in diagnosis and study ofpathogenesis of VBTIA.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
1999年第1期18-20,共3页
Journal of Apoplexy and Nervous Diseases
基金
1996年广东省科委重点课题!卫生厅资助
