摘要
目的评价达纳康治疗血管性病变所致轻度和中度认知功能减退的疗效。方法选择老年脑血管性病变后有轻、中度认知功能减退者３２例，男性２９例，女性３例，平均７７．５岁，服用达纳康口服液１ｍｌ（４０ｍｇ萃取物），每日３次，疗程１２ｗ，为开放性、非双盲、随机、单中心研究。结果达纳康可改善脑血管性病变所致轻、中度认知功能减退（Ｐ＜０．０１），并可降低血小板聚集度（Ｐ＜０．０１），对血粘度的改善不显著，不良反应轻微。结论达纳康可以改善脑血管性病变后所致轻、中度认知功能减退。
Aim Efficacy of
Tanakan,Ginkgo biloba extract,in the patients suffering from mild to moderate cognitive
impairments of vascular demenia type were studied.Method 32 patients(29 men,3 women)77 5
±7 4 years of age with the cognitive impairments due to cerebral vascular diseases were
treated with Tanakan 40 mg tid for three months.Psychophysiological investigations were
carried out on day 1 and day 120.Platelet aggregation function and blood visconsity were also
been tested.Result Tanakan can improve the cognitive functions of the patients( P <0 01);and
it also has platelet antagonistic activity( P <0 01).Conclusion The clinical efficacy of Tanakan
in cognitive impairments of cerebral vascular dementia was confirmed.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
1999年第1期27-28,共2页
Chinese Journal of Gerontology
