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200例急性心肌梗死患者急诊溶栓治疗适应证分析 被引量:10

Analysis of clinical indications for emergency thrombolysis in 200 cases with acute myocardial infarction
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摘要 目的:对急诊科急性心肌梗死(AMI)急诊溶栓治疗适应证与中华心血管病杂志编委会拟定的AMI溶栓疗法参考方案(溶栓疗法参考方案)适应证正确符合率进行比较,分析未接受溶栓治疗的原因,探讨扩大急诊溶栓治疗的适应证。方法:收集1995年2月~1997年2月急诊科收治的确诊AMI患者资料,根据溶栓疗法参考方案,分析临床决策符合率。结果:共收集200例符合AMI诊断标准的患者的总溶栓率为24.0%(48/200),溶栓正确符合率为100.0%,非溶栓正确符合率为77.0%。未接受溶栓的原因主要是因为患者来诊时间在发病后12小时以上,年龄超过70岁及非Q波心肌梗死患者。结论:急诊科溶栓具有良好的正确符合率,但溶栓条件选择较严,使较多适宜溶栓治疗的患者未得到溶栓治疗。今后仍应加强对来诊时在发病后12小时以内、年龄70岁以上及非Q波心肌梗死患者的溶栓研究。 Objective:To estimate concordance of clinical indications with consensus assessment for emergency thrombolysis in acute myocardial infarction (AMI),and to analyze the reasons for not using thrombolytic drugs.Methods:Over a period of 2 years (from Feb.1995 to Feb.1997),clinical data of patients admitted to our emergency department with diagnosis of AMI were collected and reviewed.Both thrombolysis and nonthrombolysis patients were eligible for inclusion.The concordance of emergency thrombolysis were compared with consensus.Results:The overall thrombolysis rate of 200 cases was 24 0% (48/200).The correct coincidence for patients with and without thrombolysis were 100 0% and 77 0%,respectively.The major reasons for nonthrombolytic therapy included:over 6 ̄12 hours after symptom onset,advanced age (>70 years) and nonQ wave infarction.Conclusions:This study demonstrates excellent agreement between clinical indications regarding thrombolysis and consensus.The criteria for emergency thrombolysis in AMI should be broadened,especially in those with delayed attendance more than 6 ̄12 hours after symptom onset,advanced age and nonQ wave infarction.
出处 《中国危重病急救医学》 CAS CSCD 1999年第1期36-38,共3页 Chinese Critical Care Medicine
关键词 溶栓疗法 时间窗 心肌梗塞 治疗 适应症 acute myocardial infarction\ \ emergency thrombolysis therapy\ \ timewindow
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