摘要
抑郁症的发病机制十分复杂,本文就抑郁症涉及的中枢神经递质进行综述,按照单胺类、氨基酸类、乙酰胆碱和神经肽类进行介绍,并探讨临床抑郁治疗目前遇到的挑战和处理办法及展望。
Clinical depression is viewed as a physical and psychic disease process,although a clear understanding of its etiopathology is still missing.This article introduced the development of central neurotransmitters involved in depression,containing monoamines,amino acids,acetylcholine and neuropeptides.Then discussed multiple unmet clinical needs and the strategies to treat these in depression.
作者
张文渊
李焕德
ZHANG Wen–yuan;LI Huan-de(Clinical Pharmaceutical ResearchInstitute,The Second Xiangya Hospi-tal,Central South University,Chang-sha 410011,China;School of Phar-maceutical Sciences,Central South Uni-versity,Changsha 410013,China)
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2010年第7期540-544,共5页
The Chinese Journal of Clinical Pharmacology
关键词
抑郁症
中枢神经递质
抑郁症治疗
depression
central neurotransmitter
depression treatment
