摘要
目的:观察西黄丸联合化疗治疗晚期食管癌的临床疗效。方法:晚期食管癌患者35例,随机分为治疗组18例和对照组17例,对照组,奈达铂(NDP)40mg/m2,第1-2d;5-Fu400mg/m2,第1-5d;CF200mg/m2,第1-5d。治疗组于化疗同日开始用西黄丸,化疗方案同对照组。观察两组患者在生活质量、血液学毒性、近期疗效及症状方面治疗前后的差异。结果:治疗组在生活质量提高程度、部分症状缓解率明显优于对照组,血液学毒性及近期疗效组间比较差异无显著性。结论:西黄丸可提高晚期食管癌的生活质量,缓解部分症状。
Objective: To observe the clinical effects on advanced esophageal cancer by combined Xihuang Pill with chemotherapy. Methods: Dividing 35 advanced esophageal cancer cases randomly into two groups: 18 cases in the treatment group and 17 cases in the control group. Cases in the control group were treated by nedaplatin 40mg/m^2,d1,2; 5-Fu400mg/m^2,d1-5; CF200 mg/m^2,d1-5. While the treatment with Xihuang Pill combined. The difference of quality of life, hematological toxicity, efficacy and symptoms between the two groups was observed. Results: The quality of life, remission rate of some symptom in the treatment group were much better than the control group, and the hematological toxicity and efficacy were the same. Conclusion: Xihuang Pill could improve the quality of life of advanced esophageal cancer patient, and alleviate some symptoms.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2010年第8期1302-1304,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
西黄丸
晚期食管癌
中西医结合
生活质量
症状
临床观察
Xihuang Pill
Advanced esophageal cancer
Combination of traditional and western medicine
Quality of life
Symptoms
Clinic observation