摘要
目的：总结Ⅲa期非小细胞肺癌切除术的治疗结果，探讨其临床特点及影响生存的因素。方法：采用STATA5．0软件建立病例资料数据库并进行统计分析。结果：本组术后并发症发生率为14．49％。术后30天内死亡率1．41％。5年生存率：根治术27．26％、姑息术14．20％（P＜005）；鳞癌3且．69％、腺癌10．26％（P＜0．001）。出现复发后积极治疗的1年生存率为38．89％，而不治疗无1年生存者（P＜0．05）。出现血行转移后积极治疗的2年生存率为16．75％，不治疗为4．99％（P＜0．05）。结论：手术性质、病理类型及出现复发转移后积极的治疗显著地影响预后。切缘无癌残留、综合治疗分别较切缘有癌残留、单一手术生存率高，但其差异无统计学意义。
Objective: TO evaluate the results of surgical resection in stage ill a of non －－ small cell lung cancer and Prognostic factors. Methods: 283 cases of resected stage Ⅲa non －－ small cell lung cancer were statistically analyzed using STATAS. 0 software. The survival rate was estimated using life table method. Comparison of the difference of survival between groups were made according to the log －－ rank test. ReSults: The complication rate was 14. 49%. The mortality rate was 1. 41%. The 5 －－ year survival rate was 27. 26% in radical resection and 14. 02% in palliative resection(P < 0. 05 ), and was 31. 69% in SqUamous carcinoma and 10. 26% in adenocareinoma(P < 0. 001 ). The I －－ year survival rate was 38. 89% in treated patients Of tumor recurrence and none in non －－ treated patients(P < 0. 05 ). The 2 －－ year survival rate was 16. 75% in treated metaStatic patients and4. 99% in non－treated metastatic patients(P < 0. 05 ). Conclusion: Resection nature, cell type and active heatment Of recurrence and metastasis significantly affected the prognosis. T'he prognoses were better in Patients with no －－ residual tumor in the magine and combined modality therapy was used than those patients with residual tumor in the maine and surgery alone was conducted however, there were no statistic significance.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1999年第2期205-207,共3页
Chinese Journal of Cancer
关键词
肺肿瘤
外科手术
非小细胞肺癌
Ⅲa期
Lung neoplasms/surgery
Stage Ⅲa
Lung neopalsms/non －－ amall cell
Combined modality therapy
Prognosis
